Single-nucleus RNA sequencing reveals ARHGAP28 expression of podocytes as a biomarker in human diabetic nephropathy

Single-nucleus RNA sequencing reveals ARHGAP28 expression of podocytes as a biomarker in human diabetic nephropathy

Diabetic kidney disease (DKD) represents serious diabetes-associated complications, and podocyte loss is an important histologic sign of DKD. The cellular and molecular profiles of podocytes in DKD have yet to be fully elucidated.

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Bibliographic Details
Main Authors: Zhang Fengxia, Tang Xianhu, Zeng Zhimei, Cao Chunyu, Yun Caocui, Shen Yue, Nie Chaohong, Xiong Ying, Chulian Mao, Wu Yueheng, Xu Ruiquan
Format: Article
Language:English
Published: De Gruyter 2025-04-01
Series:Open Medicine
Subjects:
diabetic kidney disease, dkd
single-nucleus rna sequencing, snrna-seq
podocyte
arhgap28
Online Access:https://doi.org/10.1515/med-2025-1146
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Summary:Diabetic kidney disease (DKD) represents serious diabetes-associated complications, and podocyte loss is an important histologic sign of DKD. The cellular and molecular profiles of podocytes in DKD have yet to be fully elucidated.
ISSN:2391-5463

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