Enhanced Disease Detection of Hairy Cell Leukaemia Through Next‐Generation Sequencing Based BRAFV600E and Phased Variant Analysis

Enhanced Disease Detection of Hairy Cell Leukaemia Through Next‐Generation Sequencing Based BRAFV600E and Phased Variant Analysis

ABSTRACT Introduction Longitudinal disease assessment by molecular techniques is not routine in hairy cell leukaemia (HCL). Combining BRAFV600E and other genomic targets through next‐generation sequencing (NGS) with phased variant analysis is a novel approach for disease detection in this setting. R...

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Bibliographic Details
Main Authors: Simon Wu, Tamia Nguyen, Imogen Caldwell, Sally Hunter, Sushmitha Kannan, Camille Santos, Yan Zhuang Yap, Clarissa Wilson, Mayani Rawicki, Constantine S. Tam, Rachel Koldej, David Ritchie, Piers Blombery
Format: Article
Language:English
Published: Wiley 2025-06-01
Series:eJHaem
Subjects:
genes
hairy cell leukaemia
immunoglobulin genes
lymphomas
molecular
NHL
Online Access:https://doi.org/10.1002/jha2.70032
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https://doi.org/10.1002/jha2.70032

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