Twelve-month efficacy of carboxymethyl-chitosan in refractory knee osteoarthritis: A randomized controlled trial (PIONEER)

Twelve-month efficacy of carboxymethyl-chitosan in refractory knee osteoarthritis: A randomized controlled trial (PIONEER)

Objectives: The 12-month efficacy and safety of a novel bioresorbable fluid implant based on CM-chitosan for intra-articular injection was evaluated in knee osteoarthritis (OA) patients with predictive factors of failure to viscosupplementation. Design: This pilot single-blind randomized controlled...

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Bibliographic Details
Main Authors: Philippe Van Overschelde, Pieter Vansintjan, Nicolas Portelange, Mickaël Chausson, Wim Weyenberg
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Osteoarthritis and Cartilage Open
Subjects:
Knee osteoarthritis
CM-Chitosan
Intra-articular injection
Refractory
Online Access:http://www.sciencedirect.com/science/article/pii/S266591312500041X
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