Muscle biopsy correlated with electromyography: study of 100 cases

To find what the correlation is and verify if is possible to avoid extensive electromyographic examination, studying only one muscle, 100 patients with neuromuscular disorders (58 primary myopathies, 32 neurogenic disorders and 10 myotonic dystrophies) were submited to quantified electromyography (E...

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Main Authors: Lineu Cesar Werneck, José Geraldo Camargo Lima
Format: Article
Language:English
Published: Thieme Revinter Publicações 1988-06-01
Series:Arquivos de Neuro-Psiquiatria
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X1988000200006&lng=en&tlng=en
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author Lineu Cesar Werneck
José Geraldo Camargo Lima
author_facet Lineu Cesar Werneck
José Geraldo Camargo Lima
author_sort Lineu Cesar Werneck
collection DOAJ
description To find what the correlation is and verify if is possible to avoid extensive electromyographic examination, studying only one muscle, 100 patients with neuromuscular disorders (58 primary myopathies, 32 neurogenic disorders and 10 myotonic dystrophies) were submited to quantified electromyography (EMG) and muscle biopsy (MB) with fresh-frozen section plus histochemistry in the same muscle, but on the opposite side. The EMG was abnormal in 98% and MB in 93% of the cases. EMG and MB had a concordance of 84.3% in the neurogenic disorders and 84.77% in the primary myopathies. A correlation of 80% was obtained between all MB and EMG (including the cases of myotonic dystrophies), regarding the origin of the pathogenic process (p<0.01). The EMG had 5% inconsistences and the MB 11%, with respect to the pathogenic process. When the myotonic dystrophy was separated from the primary myopathies and from the denervation disorders, a complete concordance was found in all MB and had only 3.4% inconsistences in the denervation disorders and 3.1% in the primary myopathies.
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spelling doaj-art-e37b869255ed4911a347c3fc8b65f91e2025-08-20T02:04:17ZengThieme Revinter PublicaçõesArquivos de Neuro-Psiquiatria1678-42271988-06-0146215616510.1590/S0004-282X1988000200006S0004-282X1988000200006Muscle biopsy correlated with electromyography: study of 100 casesLineu Cesar Werneck0José Geraldo Camargo Lima1Universidade Federal do ParanáUniversidade Federal do ParanáTo find what the correlation is and verify if is possible to avoid extensive electromyographic examination, studying only one muscle, 100 patients with neuromuscular disorders (58 primary myopathies, 32 neurogenic disorders and 10 myotonic dystrophies) were submited to quantified electromyography (EMG) and muscle biopsy (MB) with fresh-frozen section plus histochemistry in the same muscle, but on the opposite side. The EMG was abnormal in 98% and MB in 93% of the cases. EMG and MB had a concordance of 84.3% in the neurogenic disorders and 84.77% in the primary myopathies. A correlation of 80% was obtained between all MB and EMG (including the cases of myotonic dystrophies), regarding the origin of the pathogenic process (p<0.01). The EMG had 5% inconsistences and the MB 11%, with respect to the pathogenic process. When the myotonic dystrophy was separated from the primary myopathies and from the denervation disorders, a complete concordance was found in all MB and had only 3.4% inconsistences in the denervation disorders and 3.1% in the primary myopathies.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X1988000200006&lng=en&tlng=en
spellingShingle Lineu Cesar Werneck
José Geraldo Camargo Lima
Muscle biopsy correlated with electromyography: study of 100 cases
Arquivos de Neuro-Psiquiatria
title Muscle biopsy correlated with electromyography: study of 100 cases
title_full Muscle biopsy correlated with electromyography: study of 100 cases
title_fullStr Muscle biopsy correlated with electromyography: study of 100 cases
title_full_unstemmed Muscle biopsy correlated with electromyography: study of 100 cases
title_short Muscle biopsy correlated with electromyography: study of 100 cases
title_sort muscle biopsy correlated with electromyography study of 100 cases
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X1988000200006&lng=en&tlng=en
work_keys_str_mv AT lineucesarwerneck musclebiopsycorrelatedwithelectromyographystudyof100cases
AT josegeraldocamargolima musclebiopsycorrelatedwithelectromyographystudyof100cases