Retinal prolactin isoform PRLΔE1 sustains rod disease in inherited retinal degenerations
Abstract PRLΔE1, a retina-specific isoform of prolactin, is expressed in multiple and diverse forms of canine inherited retinal degeneration (IRD). We find that while PRLΔE1 expression in rods is not associated with the initial phase of disease characterized by acute photoreceptor cell death, it is...
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| Main Authors: | Raghavi Sudharsan, Jennifer Kwok, Malgorzata Swider, Alexander Sumaroka, Gustavo D. Aguirre, Artur V. Cideciyan, William A. Beltran |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2024-09-01
|
| Series: | Cell Death and Disease |
| Online Access: | https://doi.org/10.1038/s41419-024-07070-1 |
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