Elucidating cardiomyocyte heterogeneity and maturation dynamics through integrated single-cell and spatial transcriptomics

Elucidating cardiomyocyte heterogeneity and maturation dynamics through integrated single-cell and spatial transcriptomics

Summary: The intricate development and functionality of the mammalian heart are influenced by the heterogeneous nature of cardiomyocytes (CMs). In this study, single-cell and spatial transcriptomics were utilized to analyze cells from neonatal mouse hearts, resulting in a comprehensive atlas delinea...

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Bibliographic Details
Main Authors: Xiaoying Wang, Lizhi Cao, Rui Chang, Junwei Shen, Linlin Ma, Yanfei Li
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:iScience
Subjects:
Cell biology
Omics
Transcriptomics
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004224028232
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