Medium-sized protein language models perform well at transfer learning on realistic datasets

Abstract Protein language models (pLMs) can offer deep insights into evolutionary and structural properties of proteins. While larger models, such as the 15 billion parameter model ESM-2, promise to capture more complex patterns in sequence space, they also present practical challenges due to their...

Full description

Saved in:
Bibliographic Details
Main Authors: Luiz C. Vieira, Morgan L. Handojo, Claus O. Wilke
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Online Access:https://doi.org/10.1038/s41598-025-05674-x
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items