Prodigiosin: A Potential Eco-Friendly Insecticide for Sustainable Crop Protection
Globally, insect pests adversely affect approximately 75% of the most important crops. However, the widespread use of chemical insecticides has significant drawbacks, including non-specific biological activity, toxicity to humans, detrimental effects on beneficial insects, and the rapid development...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2025-05-01
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| Series: | Colorants |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2079-6447/4/2/18 |
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| Summary: | Globally, insect pests adversely affect approximately 75% of the most important crops. However, the widespread use of chemical insecticides has significant drawbacks, including non-specific biological activity, toxicity to humans, detrimental effects on beneficial insects, and the rapid development of resistance. In this context, prodigiosin—a tripyrrolic secondary metabolite produced by various microorganisms—emerges as a promising alternative due to its favourable properties, such as being non-toxic, environmentally safe, non-irritant, and non-allergenic, and having non-carcinogenic potential. Prodigiosin has demonstrated insecticidal efficiency against pests at various developmental stages. Studies suggest that prodigiosin inhibits enzymes like acetylcholine esterase, protease, and acid phosphatase and induces oxidative stress. This review explores the potential of prodigiosin as an eco-friendly insecticide, discussing its production, extraction, and purification processes and its advantages, disadvantages, and mechanism of action, and future perspectives. Special emphasis is given to using non-pathogenic strains to mitigate biosafety concerns. |
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| ISSN: | 2079-6447 |