Crystal Structure of Phototoxic Orange Fluorescent Proteins with a Tryptophan-Based Chromophore.

Crystal Structure of Phototoxic Orange Fluorescent Proteins with a Tryptophan-Based Chromophore.

Phototoxic fluorescent proteins represent a sparse group of genetically encoded photosensitizers that could be used for precise light-induced inactivation of target proteins, DNA damage, and cell killing. Only two such GFP-based fluorescent proteins (FPs), KillerRed and its monomeric variant SuperNo...

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Main Authors: Nadya V Pletneva, Vladimir Z Pletnev, Karen S Sarkisyan, Dmitry A Gorbachev, Evgeny S Egorov, Alexander S Mishin, Konstantin A Lukyanov, Zbigniew Dauter, Sergei Pletnev
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0145740
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