Severe Congenital Toxoplasmosis: A Case Report and Strain Characterization
We report a fatal congenital toxoplasmosis case in an Iranian woman in the south of Iran. A pregnant mother had been admitted at the 15th week of her pregnancy on account of a febrile illness, symptoms of common cold, and enlargement of submandibular lymph nodes. Serological testing of the mother’s...
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| Format: | Article |
| Language: | English |
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Wiley
2015-01-01
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| Series: | Case Reports in Infectious Diseases |
| Online Access: | http://dx.doi.org/10.1155/2015/851085 |
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| _version_ | 1832556227754721280 |
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| author | Bahador Sarkari Samaneh Abdolahi Khabisi |
| author_facet | Bahador Sarkari Samaneh Abdolahi Khabisi |
| author_sort | Bahador Sarkari |
| collection | DOAJ |
| description | We report a fatal congenital toxoplasmosis case in an Iranian woman in the south of Iran. A pregnant mother had been admitted at the 15th week of her pregnancy on account of a febrile illness, symptoms of common cold, and enlargement of submandibular lymph nodes. Serological testing of the mother’s serum revealed positive IgG and IgM anti-Toxoplasma antibodies. Amniotic fluid was taken and evaluated by polymerase chain reaction (PCR) assay with a direct amplification of the Toxoplasma URPT gene which was found to be positive. Sequencing and analysis of PCR product revealed that the isolate has the most similarity with type I of Toxoplasma gondii. Fetal scan showed anomaly in fetus including mild hydrocephaly. Termination of the pregnancy was suggested by the physician and pregnancy was terminated 178 days after conception. |
| format | Article |
| id | doaj-art-e369c6ad2f3341859797630dd5a15779 |
| institution | Kabale University |
| issn | 2090-6625 2090-6633 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Infectious Diseases |
| spelling | doaj-art-e369c6ad2f3341859797630dd5a157792025-02-03T05:46:05ZengWileyCase Reports in Infectious Diseases2090-66252090-66332015-01-01201510.1155/2015/851085851085Severe Congenital Toxoplasmosis: A Case Report and Strain CharacterizationBahador Sarkari0Samaneh Abdolahi Khabisi1Basic Sciences in Infectious Diseases Research Center, Shiraz University of Medical Sciences, Shiraz, IranDepartment of Parasitology and Mycology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, IranWe report a fatal congenital toxoplasmosis case in an Iranian woman in the south of Iran. A pregnant mother had been admitted at the 15th week of her pregnancy on account of a febrile illness, symptoms of common cold, and enlargement of submandibular lymph nodes. Serological testing of the mother’s serum revealed positive IgG and IgM anti-Toxoplasma antibodies. Amniotic fluid was taken and evaluated by polymerase chain reaction (PCR) assay with a direct amplification of the Toxoplasma URPT gene which was found to be positive. Sequencing and analysis of PCR product revealed that the isolate has the most similarity with type I of Toxoplasma gondii. Fetal scan showed anomaly in fetus including mild hydrocephaly. Termination of the pregnancy was suggested by the physician and pregnancy was terminated 178 days after conception.http://dx.doi.org/10.1155/2015/851085 |
| spellingShingle | Bahador Sarkari Samaneh Abdolahi Khabisi Severe Congenital Toxoplasmosis: A Case Report and Strain Characterization Case Reports in Infectious Diseases |
| title | Severe Congenital Toxoplasmosis: A Case Report and Strain Characterization |
| title_full | Severe Congenital Toxoplasmosis: A Case Report and Strain Characterization |
| title_fullStr | Severe Congenital Toxoplasmosis: A Case Report and Strain Characterization |
| title_full_unstemmed | Severe Congenital Toxoplasmosis: A Case Report and Strain Characterization |
| title_short | Severe Congenital Toxoplasmosis: A Case Report and Strain Characterization |
| title_sort | severe congenital toxoplasmosis a case report and strain characterization |
| url | http://dx.doi.org/10.1155/2015/851085 |
| work_keys_str_mv | AT bahadorsarkari severecongenitaltoxoplasmosisacasereportandstraincharacterization AT samanehabdolahikhabisi severecongenitaltoxoplasmosisacasereportandstraincharacterization |