An Efficient One-Pot Synthesis of 1, 5-Benzodiazepine Derivatives Catalyzed by TBAB under Mild Conditions

2,3-Dihydro-1H-1,5-benzodiazepines were synthesized by reaction of o-phenylenediamine with ketones (acyclic / cyclic) under solvent free conditions in the presence of tetra butyl ammonium bromide (TBAB) in short reaction time with excellent yield.

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Main Authors: Mohammad A. Baseer, Asgar Jafar Khan
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:E-Journal of Chemistry
Online Access:http://dx.doi.org/10.1155/2012/657439
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author Mohammad A. Baseer
Asgar Jafar Khan
author_facet Mohammad A. Baseer
Asgar Jafar Khan
author_sort Mohammad A. Baseer
collection DOAJ
description 2,3-Dihydro-1H-1,5-benzodiazepines were synthesized by reaction of o-phenylenediamine with ketones (acyclic / cyclic) under solvent free conditions in the presence of tetra butyl ammonium bromide (TBAB) in short reaction time with excellent yield.
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institution Kabale University
issn 0973-4945
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publishDate 2012-01-01
publisher Wiley
record_format Article
series E-Journal of Chemistry
spelling doaj-art-e3691b4770c54f1497f18c7740c1ed7f2025-08-20T03:26:31ZengWileyE-Journal of Chemistry0973-49452090-98102012-01-019140741410.1155/2012/657439An Efficient One-Pot Synthesis of 1, 5-Benzodiazepine Derivatives Catalyzed by TBAB under Mild ConditionsMohammad A. Baseer0Asgar Jafar Khan1Organic Chemistry Research Laboratory, Yeshwant Mahavidyalaya, Nanded-431602, IndiaLaboratory of Organic Synthesis, Milliya College, Beed-431122, India2,3-Dihydro-1H-1,5-benzodiazepines were synthesized by reaction of o-phenylenediamine with ketones (acyclic / cyclic) under solvent free conditions in the presence of tetra butyl ammonium bromide (TBAB) in short reaction time with excellent yield.http://dx.doi.org/10.1155/2012/657439
spellingShingle Mohammad A. Baseer
Asgar Jafar Khan
An Efficient One-Pot Synthesis of 1, 5-Benzodiazepine Derivatives Catalyzed by TBAB under Mild Conditions
E-Journal of Chemistry
title An Efficient One-Pot Synthesis of 1, 5-Benzodiazepine Derivatives Catalyzed by TBAB under Mild Conditions
title_full An Efficient One-Pot Synthesis of 1, 5-Benzodiazepine Derivatives Catalyzed by TBAB under Mild Conditions
title_fullStr An Efficient One-Pot Synthesis of 1, 5-Benzodiazepine Derivatives Catalyzed by TBAB under Mild Conditions
title_full_unstemmed An Efficient One-Pot Synthesis of 1, 5-Benzodiazepine Derivatives Catalyzed by TBAB under Mild Conditions
title_short An Efficient One-Pot Synthesis of 1, 5-Benzodiazepine Derivatives Catalyzed by TBAB under Mild Conditions
title_sort efficient one pot synthesis of 1 5 benzodiazepine derivatives catalyzed by tbab under mild conditions
url http://dx.doi.org/10.1155/2012/657439
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AT asgarjafarkhan anefficientonepotsynthesisof15benzodiazepinederivativescatalyzedbytbabundermildconditions
AT mohammadabaseer efficientonepotsynthesisof15benzodiazepinederivativescatalyzedbytbabundermildconditions
AT asgarjafarkhan efficientonepotsynthesisof15benzodiazepinederivativescatalyzedbytbabundermildconditions