Using the Simcyp R Package for PBPK Simulation Workflows With the Simcyp Simulator

Using the Simcyp R Package for PBPK Simulation Workflows With the Simcyp Simulator

ABSTRACT Physiologically based pharmacokinetic and pharmacodynamic (PBPK/PD) modeling aims to understand how a drug is absorbed, distributed, metabolized, excreted, and acts in a human or animal body. The Simcyp Simulator is a well‐known commercial PBPK/PD simulation software offering many options....

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Bibliographic Details
Main Authors: Anthonia M. Onasanwo, Naresh Mittapelly, Laura Shireman, Barry Vinden, Kevin McNally, James Craig, Frederic Y. Bois
Format: Article
Language:English
Published: Wiley 2025-05-01
Series:CPT: Pharmacometrics & Systems Pharmacology
Subjects:
PBPK modeling
R statistical software
simulation workflow
Online Access:https://doi.org/10.1002/psp4.70022
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