Trauma resuscitation with Low-Titer Group O Whole Blood Or Products: study protocol for a randomized clinical trial (the TROOP trial)

Trauma resuscitation with Low-Titer Group O Whole Blood Or Products: study protocol for a randomized clinical trial (the TROOP trial)

Abstract Background Hemorrhage is the most common cause of potentially preventable death after injury. Balanced transfusion with red blood cells, plasma, and platelets (component therapy, CT) has been shown to reduce mortality, and is the standard of care. Low-Titer Group O Whole Blood (LTOWB) is an...

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Main Authors: Jan O. Jansen, Claudia Pedroza, Luis Leon Novelo, Tianyao Hao, Gina R. DeWildt, Charles F. Coton, Kiran Mansoor, Shannon W. Stephens, Marisa B. Marques, James R. Stubbs, Jillian R. Richter, Henry E. Wang, John B. Holcomb, Stacia M. DeSantis
Format: Article
Language:English
Published: BMC 2025-08-01
Series:Trials
Subjects:
Trauma
Injury
Resuscitation
Low-Titer Group O Whole Blood
Component therapy
Online Access:https://doi.org/10.1186/s13063-025-08971-y
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https://doi.org/10.1186/s13063-025-08971-y

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