Papillary Adenocarcinoma

Gastric papillary adenocarcinoma is one of the histological variants of gastric cancer that shows more aggressive clinicopathological behavior compared to tubular adenocarcinoma. Previous studies have reported higher lymphovascular and submucosal invasion rates for papillary adenocarcionoma than tho...

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Main Authors: Tae-Se Kim, Byung-Hoon Min
Format: Article
Language:English
Published: Korean College of Helicobacter and Upper Gastrointestinal Research 2021-06-01
Series:The Korean Journal of Helicobacter and Upper Gastrointestinal Research
Subjects:
Online Access:http://www.helicojournal.org/upload/pdf/kjhugr-2021-0009.pdf
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author Tae-Se Kim
Byung-Hoon Min
author_facet Tae-Se Kim
Byung-Hoon Min
author_sort Tae-Se Kim
collection DOAJ
description Gastric papillary adenocarcinoma is one of the histological variants of gastric cancer that shows more aggressive clinicopathological behavior compared to tubular adenocarcinoma. Previous studies have reported higher lymphovascular and submucosal invasion rates for papillary adenocarcionoma than those of tubular adenocarcinoma. However, the current guidelines categorize papillary adenocarcinoma and tubular adenocarcinoma together as differentiated-type tumor and have recommended the same endoscopic submucosal dissection criteria. Thus, concerns have been raised regarding the appropriateness of the current policy. To validate the current guidelines, the lymph node metastasis rate from surgical specimen studies as well as the long-term outcomes of endoscopic submucosal dissection for papillary adenocarcinomas need to be taken into consideration. In this review, I aimed to review the current understanding of the clinical and pathological features of papillary adenocarcinoma. In addition, I aimed to generate an integrated view regarding the outcomes of endoscopic submucosal dissection and surgery for papillary adenocarcinoma in order to evaluate the appropriateness of the current guidelines.
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spelling doaj-art-e35f04f35e994e80aecc1b8cf947389f2025-08-20T02:51:04ZengKorean College of Helicobacter and Upper Gastrointestinal ResearchThe Korean Journal of Helicobacter and Upper Gastrointestinal Research1738-33312021-06-0121212212610.7704/kjhugr.2021.0009672Papillary AdenocarcinomaTae-Se Kim0Byung-Hoon Min1Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, KoreaDepartment of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, KoreaGastric papillary adenocarcinoma is one of the histological variants of gastric cancer that shows more aggressive clinicopathological behavior compared to tubular adenocarcinoma. Previous studies have reported higher lymphovascular and submucosal invasion rates for papillary adenocarcionoma than those of tubular adenocarcinoma. However, the current guidelines categorize papillary adenocarcinoma and tubular adenocarcinoma together as differentiated-type tumor and have recommended the same endoscopic submucosal dissection criteria. Thus, concerns have been raised regarding the appropriateness of the current policy. To validate the current guidelines, the lymph node metastasis rate from surgical specimen studies as well as the long-term outcomes of endoscopic submucosal dissection for papillary adenocarcinomas need to be taken into consideration. In this review, I aimed to review the current understanding of the clinical and pathological features of papillary adenocarcinoma. In addition, I aimed to generate an integrated view regarding the outcomes of endoscopic submucosal dissection and surgery for papillary adenocarcinoma in order to evaluate the appropriateness of the current guidelines.http://www.helicojournal.org/upload/pdf/kjhugr-2021-0009.pdfendoscopic submucosal dissectionpapillary adenocarcinomastomach neoplasms
spellingShingle Tae-Se Kim
Byung-Hoon Min
Papillary Adenocarcinoma
The Korean Journal of Helicobacter and Upper Gastrointestinal Research
endoscopic submucosal dissection
papillary adenocarcinoma
stomach neoplasms
title Papillary Adenocarcinoma
title_full Papillary Adenocarcinoma
title_fullStr Papillary Adenocarcinoma
title_full_unstemmed Papillary Adenocarcinoma
title_short Papillary Adenocarcinoma
title_sort papillary adenocarcinoma
topic endoscopic submucosal dissection
papillary adenocarcinoma
stomach neoplasms
url http://www.helicojournal.org/upload/pdf/kjhugr-2021-0009.pdf
work_keys_str_mv AT taesekim papillaryadenocarcinoma
AT byunghoonmin papillaryadenocarcinoma