The Pseudomonas aeruginosa T3SS can contribute to traversal of an in situ epithelial multilayer independently of the T3SS needle

The Pseudomonas aeruginosa T3SS can contribute to traversal of an in situ epithelial multilayer independently of the T3SS needle

ABSTRACT Multilayered epithelia lining our tissue surfaces normally resist traversal by opportunistic bacteria. Previously, we developed a strategy to experimentally perturb this resistance in situ in the corneas of mouse eyes and used it to show that traversal of a multilayered epithelium by Pseudo...

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Bibliographic Details
Main Authors: Eric Jedel, Daniel Schator, Naren G. Kumar, Aaron B. Sullivan, Arne Rietsch, David J. Evans, Suzanne M. J. Fleiszig
Format: Article
Language:English
Published: American Society for Microbiology 2025-04-01
Series:mBio
Subjects:
Pseudomonas aeruginosa
epithelium traversal
type three secretion system
in situ
T3SS needle
T3SS translocon
Online Access:https://journals.asm.org/doi/10.1128/mbio.00266-25
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