Pseudomesotheliomatous carcinoma of the lung
Introduction. Pseudomesotheliomatous lung carcinoma is a special, rare entity characterized by large pleural growth and minor invasion of lung tissue. Clinically, radiologically, macroscopically and even histologically this tumor can be misdiagnosed as malignant pleural carcinoma. Case report. We re...
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Ministry of Defence of the Republic of Serbia, University of Defence, Belgrade
2016-01-01
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| Series: | Vojnosanitetski Pregled |
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| Online Access: | http://www.doiserbia.nb.rs/img/doi/0042-8450/2016/0042-84501600138V.pdf |
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| author | Vuković Jelena Plavec Goran Aćimović Slobodan Jović Milena Stojsavljević Marko Trimčev Jovana Nikolajević Sanja Skuletić Vesna Lončarević Olivera Živković Vladan Zolotarevska Lidija Cerović Snežana |
| author_facet | Vuković Jelena Plavec Goran Aćimović Slobodan Jović Milena Stojsavljević Marko Trimčev Jovana Nikolajević Sanja Skuletić Vesna Lončarević Olivera Živković Vladan Zolotarevska Lidija Cerović Snežana |
| author_sort | Vuković Jelena |
| collection | DOAJ |
| description | Introduction. Pseudomesotheliomatous lung carcinoma is a special, rare entity characterized by large pleural growth and minor invasion of lung tissue. Clinically, radiologically, macroscopically and even histologically this tumor can be misdiagnosed as malignant pleural carcinoma. Case report. We represent a 64-year-old male patient, former smoker. Due to difficulties in the form of dry cough, feeling of dis-comfort and pain in the right hemithorax, fatigue, heavy breathing, sweating, fever up to 39.6°C the patient was treated as with combined antibiotic therapy (macrolides, cephalosporins and penicillin), but without improving of his condition. Chest radiography showed a shadow of pleural effusion by the height of the front end of the third right rib. Chest MSCT showed the extremely thickened pleura apically and to the posterior along the upper right lobe in addition to existence of massive pleural effusion. Subpleural condensation of parenchyma ranging about 30 mm was described in the upper right lobe. Cytological analysis of the pleural effusion showed the presence of malignant cells impossible to differentiate whether they were metastasis of adenocarcinoma or malignant pleural mesothelioma. By histochemical and immunohistohemical analyses of a pleural sample, pseudomesotheliomataus lung adenocarcinoma was diagnosed. Conclusion. Pseudomesotheliomataus carcinoma of the lungs can be a diagnostic problem. Its diagnosis is based on recognition of histopathological characteristics which enable its discernment from the epithelial variant of malignant pleural mesothelioma. |
| format | Article |
| id | doaj-art-e35630f38bec4021a52cd2cd5e9b3704 |
| institution | Kabale University |
| issn | 0042-8450 2406-0720 |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Ministry of Defence of the Republic of Serbia, University of Defence, Belgrade |
| record_format | Article |
| series | Vojnosanitetski Pregled |
| spelling | doaj-art-e35630f38bec4021a52cd2cd5e9b37042025-08-20T03:26:30ZengMinistry of Defence of the Republic of Serbia, University of Defence, BelgradeVojnosanitetski Pregled0042-84502406-07202016-01-0173121168117210.2298/VSP150811138V0042-84501600138VPseudomesotheliomatous carcinoma of the lungVuković Jelena0Plavec Goran1Aćimović Slobodan2Jović Milena3Stojsavljević Marko4Trimčev Jovana5Nikolajević Sanja6Skuletić Vesna7Lončarević Olivera8Živković Vladan9Zolotarevska Lidija10Cerović Snežana11Military Medical Academy, Clinic for Pulmology, BelgradeMilitary Medical Academy, Clinic for Pulmology, Belgrade + University of Defence, Faculty of Medicine of the Military Medical Academy, BelgradeMilitary Medical Academy, Clinic for Pulmology, BelgradeUniversity of Defence, Faculty of Medicine of the Military Medical Academy, BelgradeMilitary Medical Academy, Clinic for Pulmology, BelgradeUniversity of Defence, Faculty of Medicine of the Military Medical Academy, BelgradeUniversity of Defence, Faculty of Medicine of the Military Medical Academy, BelgradeUniversity of Defence, Faculty of Medicine of the Military Medical Academy, Belgrade + Military Medical Academy, Institute of Pathology and Forensic MedicineMilitary Medical Academy, Clinic for Pulmology, BelgradeMilitary Medical Academy, Clinic for Pulmology, BelgradeUniversity of Defence, Faculty of Medicine of the Military Medical Academy, Belgrade + Military Medical Academy, Institute of Pathology and Forensic MedicineUniversity of Defence, Faculty of Medicine of the Military Medical Academy, Belgrade + Military Medical Academy, Institute of Pathology and Forensic MedicineIntroduction. Pseudomesotheliomatous lung carcinoma is a special, rare entity characterized by large pleural growth and minor invasion of lung tissue. Clinically, radiologically, macroscopically and even histologically this tumor can be misdiagnosed as malignant pleural carcinoma. Case report. We represent a 64-year-old male patient, former smoker. Due to difficulties in the form of dry cough, feeling of dis-comfort and pain in the right hemithorax, fatigue, heavy breathing, sweating, fever up to 39.6°C the patient was treated as with combined antibiotic therapy (macrolides, cephalosporins and penicillin), but without improving of his condition. Chest radiography showed a shadow of pleural effusion by the height of the front end of the third right rib. Chest MSCT showed the extremely thickened pleura apically and to the posterior along the upper right lobe in addition to existence of massive pleural effusion. Subpleural condensation of parenchyma ranging about 30 mm was described in the upper right lobe. Cytological analysis of the pleural effusion showed the presence of malignant cells impossible to differentiate whether they were metastasis of adenocarcinoma or malignant pleural mesothelioma. By histochemical and immunohistohemical analyses of a pleural sample, pseudomesotheliomataus lung adenocarcinoma was diagnosed. Conclusion. Pseudomesotheliomataus carcinoma of the lungs can be a diagnostic problem. Its diagnosis is based on recognition of histopathological characteristics which enable its discernment from the epithelial variant of malignant pleural mesothelioma.http://www.doiserbia.nb.rs/img/doi/0042-8450/2016/0042-84501600138V.pdflung neoplasmsadenocarcinomadiagnosisdiagnosis differentialmesothelioma, malignantprognosistreatment outcome |
| spellingShingle | Vuković Jelena Plavec Goran Aćimović Slobodan Jović Milena Stojsavljević Marko Trimčev Jovana Nikolajević Sanja Skuletić Vesna Lončarević Olivera Živković Vladan Zolotarevska Lidija Cerović Snežana Pseudomesotheliomatous carcinoma of the lung Vojnosanitetski Pregled lung neoplasms adenocarcinoma diagnosis diagnosis differential mesothelioma, malignant prognosis treatment outcome |
| title | Pseudomesotheliomatous carcinoma of the lung |
| title_full | Pseudomesotheliomatous carcinoma of the lung |
| title_fullStr | Pseudomesotheliomatous carcinoma of the lung |
| title_full_unstemmed | Pseudomesotheliomatous carcinoma of the lung |
| title_short | Pseudomesotheliomatous carcinoma of the lung |
| title_sort | pseudomesotheliomatous carcinoma of the lung |
| topic | lung neoplasms adenocarcinoma diagnosis diagnosis differential mesothelioma, malignant prognosis treatment outcome |
| url | http://www.doiserbia.nb.rs/img/doi/0042-8450/2016/0042-84501600138V.pdf |
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