Expression Profile of Tyrosine Phosphatases in HER2 Breast Cancer Cells and Tumors

Background: HER2-overexpression promotes malignancy by modulating signalling molecules, which include PTPs/DSPs (protein tyrosine and dual-specificity phosphatases). Our aim was to identify PTPs/DSPs displaying HER2-associated expression alterations.

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Main Authors: Maria Antonietta Lucci, Rosaria Orlandi, Tiziana Triulzi, Elda Tagliabue, Andrea Balsari, Emma Villa-Moruzzi
Format: Article
Language:English
Published: Wiley 2010-01-01
Series:Cellular Oncology
Online Access:http://dx.doi.org/10.3233/CLO-2010-0520
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author Maria Antonietta Lucci
Rosaria Orlandi
Tiziana Triulzi
Elda Tagliabue
Andrea Balsari
Emma Villa-Moruzzi
author_facet Maria Antonietta Lucci
Rosaria Orlandi
Tiziana Triulzi
Elda Tagliabue
Andrea Balsari
Emma Villa-Moruzzi
author_sort Maria Antonietta Lucci
collection DOAJ
description Background: HER2-overexpression promotes malignancy by modulating signalling molecules, which include PTPs/DSPs (protein tyrosine and dual-specificity phosphatases). Our aim was to identify PTPs/DSPs displaying HER2-associated expression alterations.
format Article
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institution Kabale University
issn 1570-5870
1875-8606
language English
publishDate 2010-01-01
publisher Wiley
record_format Article
series Cellular Oncology
spelling doaj-art-e353cc3cb84b4b6e8db00e416b68008b2025-02-03T01:13:11ZengWileyCellular Oncology1570-58701875-86062010-01-01325-636137210.3233/CLO-2010-0520Expression Profile of Tyrosine Phosphatases in HER2 Breast Cancer Cells and TumorsMaria Antonietta Lucci0Rosaria Orlandi1Tiziana Triulzi2Elda Tagliabue3Andrea Balsari4Emma Villa-Moruzzi5Department of Experimental Pathology, University of Pisa, Pisa, ItalyMolecular Biology Unit, Department of Experimental Oncology, Istituto Nazionale Tumori, Milan, ItalyMolecular Biology Unit, Department of Experimental Oncology, Istituto Nazionale Tumori, Milan, ItalyMolecular Biology Unit, Department of Experimental Oncology, Istituto Nazionale Tumori, Milan, ItalyDepartment of Human Morphology and Biomedical Sciences, University of Milan, Milan, ItalyDepartment of Experimental Pathology, University of Pisa, Pisa, ItalyBackground: HER2-overexpression promotes malignancy by modulating signalling molecules, which include PTPs/DSPs (protein tyrosine and dual-specificity phosphatases). Our aim was to identify PTPs/DSPs displaying HER2-associated expression alterations.http://dx.doi.org/10.3233/CLO-2010-0520
spellingShingle Maria Antonietta Lucci
Rosaria Orlandi
Tiziana Triulzi
Elda Tagliabue
Andrea Balsari
Emma Villa-Moruzzi
Expression Profile of Tyrosine Phosphatases in HER2 Breast Cancer Cells and Tumors
Cellular Oncology
title Expression Profile of Tyrosine Phosphatases in HER2 Breast Cancer Cells and Tumors
title_full Expression Profile of Tyrosine Phosphatases in HER2 Breast Cancer Cells and Tumors
title_fullStr Expression Profile of Tyrosine Phosphatases in HER2 Breast Cancer Cells and Tumors
title_full_unstemmed Expression Profile of Tyrosine Phosphatases in HER2 Breast Cancer Cells and Tumors
title_short Expression Profile of Tyrosine Phosphatases in HER2 Breast Cancer Cells and Tumors
title_sort expression profile of tyrosine phosphatases in her2 breast cancer cells and tumors
url http://dx.doi.org/10.3233/CLO-2010-0520
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AT tizianatriulzi expressionprofileoftyrosinephosphatasesinher2breastcancercellsandtumors
AT eldatagliabue expressionprofileoftyrosinephosphatasesinher2breastcancercellsandtumors
AT andreabalsari expressionprofileoftyrosinephosphatasesinher2breastcancercellsandtumors
AT emmavillamoruzzi expressionprofileoftyrosinephosphatasesinher2breastcancercellsandtumors