Mechanisms and therapeutics of insulin signaling transduction genes in diabetic cardiomyopathy: a comprehensive updated review

Mechanisms and therapeutics of insulin signaling transduction genes in diabetic cardiomyopathy: a comprehensive updated review

Diabetic cardiomyopathy (DCM), a complication of type 2 diabetes mellitus (T2DM), is closely associated with key genes in the insulin signaling pathway. Insulin regulates cellular metabolism and growth under normal conditions by activating downstream signaling pathways through its receptors. Nonethe...

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Bibliographic Details
Main Authors: Yufeng He, Xi Yang, Xinghui He, Guoshuang Wang, Chuang Li, Ping Yuan, Chunhong Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Endocrinology
Subjects:
diabetic cardiomyopathy
heart failure
insulin signaling
gene
treatment
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2025.1589695/full
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