Cardiovascular status and echocardiographic changes in survivors of COVID-19 pneumonia three months after hospital discharge

Coronavirus disease 2019 (COVID-19) affects the function of all organs and systems. Today, studying the effect of COVID-19 on cardiovascular system, including on echocardiographic characteristics, is relevant.Aim. To study the prevalence of symptoms, cardiovascular disease and changes in echocardiog...

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Main Authors: D. V. Krinochkin, E. I. Yaroslavskaya, N. E. Shirokov, E. P. Gultyaeva, I. R. Krinochkina, I. O. Korovina, A. V. Mamarina, N. A. Osokina, N. N. Melnikov, T. A. Trifanova, E. A. Gorbatenko, T. I. Petelina
Format: Article
Language:Russian
Published: «FIRMA «SILICEA» LLC 2021-10-01
Series:Российский кардиологический журнал
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Online Access:https://russjcardiol.elpub.ru/jour/article/view/4656
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author D. V. Krinochkin
E. I. Yaroslavskaya
N. E. Shirokov
E. P. Gultyaeva
I. R. Krinochkina
I. O. Korovina
A. V. Mamarina
N. A. Osokina
N. N. Melnikov
T. A. Trifanova
E. A. Gorbatenko
T. I. Petelina
author_facet D. V. Krinochkin
E. I. Yaroslavskaya
N. E. Shirokov
E. P. Gultyaeva
I. R. Krinochkina
I. O. Korovina
A. V. Mamarina
N. A. Osokina
N. N. Melnikov
T. A. Trifanova
E. A. Gorbatenko
T. I. Petelina
author_sort D. V. Krinochkin
collection DOAJ
description Coronavirus disease 2019 (COVID-19) affects the function of all organs and systems. Today, studying the effect of COVID-19 on cardiovascular system, including on echocardiographic characteristics, is relevant.Aim. To study the prevalence of symptoms, cardiovascular disease and changes in echocardiographic data in persons after documented COVID-19 pneumonia 3 months after discharge from the hospital.Material and methods. The study included 106 patients after documented COVID-19 pneumonia. The patients underwent a comprehensive examination during hospitalization and 3 months±2 weeks after discharge from the hospital. The mean age of participants was 47±16 years (19-84 years); 49% of subjects were women.Results. Three months after hospital discharge, the symptoms persisted in 86% of examined patients. There were significant echocardiographic changes as follows: a decrease in LV end-diastolic, end-systolic and stroke volume (113,8±26,8 ml vs 93,5±29,4 ml; 37,7±13,0 ml vs 31,3±14,2 ml; 77,2±17,8 ml vs 62,2±18,7 ml, respectively, p<0,001 for all). The right ventricular anteroposterior dimension and the pulmonary trunk diameter decreased over time (26,0 [24,0-29,3] mm vs 25,0 [23,0-27,0] mm, p=0,004; 21,7±3,6 mm vs 18,7±2,5 mm, p<0,001), the same as the pulmonary artery systolic pressure, estimated by tricuspid regurgitation gradient (28,0 [25,0-32,25] mm Hg vs 21,5 [17,0-25,0] mm Hg). The right atrial volume (42,0 [37,0-50,0] m><0,001), the same as the pulmonary artery systolic pressure, estimated by tricuspid regurgitation gradient (28,0 [25,0-32,25] mm Hg vs 21,5 [17,0-25,0] mm Hg). The right atrial volume (42,0 [37,0-50,0] ml vs 31,0 [22,0-36,5] ml, p<0,001) a><0,001) and maximum width (36,1±4,6 mm vs 34,5±6,5 mm, p=0,023) decreased, while the right atrial maximum length increased (46,7±6,8 mm vs 48,6±7,1 mm, p=0,021).Conclusion. In survivors of COVID-19 pneumonia three months after hospital discharge, complaints persisted in 86% of cases. Cardiovascular diseases were detected in 52% of participants, including hypertension in 48,1% and coronary artery disease in 15,1%. Compared with in-hospital data, the echocardiographic characteristics improved, which was expressed mainly in a decrease in right heart load.
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spelling doaj-art-e349e66804704ac09122ca692ff574742025-08-20T03:21:31Zrus«FIRMA «SILICEA» LLCРоссийский кардиологический журнал1560-40712618-76202021-10-0126910.15829/1560-4071-2021-46563355Cardiovascular status and echocardiographic changes in survivors of COVID-19 pneumonia three months after hospital dischargeD. V. Krinochkin0E. I. Yaroslavskaya1N. E. Shirokov2E. P. Gultyaeva3I. R. Krinochkina4I. O. Korovina5A. V. Mamarina6N. A. Osokina7N. N. Melnikov8T. A. Trifanova9E. A. Gorbatenko10T. I. Petelina11Tyumen Cardiology Research Center, Tomsk National Research Medical CenterTyumen Cardiology Research Center, Tomsk National Research Medical CenterTyumen Cardiology Research Center, Tomsk National Research Medical CenterTyumen Cardiology Research Center, Tomsk National Research Medical CenterTyumen State Medical University; City Clinical Hospital № 1City Clinical Hospital № 1Tyumen Cardiology Research Center, Tomsk National Research Medical CenterTyumen State Medical UniversityCity Clinical Hospital № 2Tyumen Cardiology Research Center, Tomsk National Research Medical CenterTyumen Cardiology Research Center, Tomsk National Research Medical CenterTyumen Cardiology Research Center, Tomsk National Research Medical CenterCoronavirus disease 2019 (COVID-19) affects the function of all organs and systems. Today, studying the effect of COVID-19 on cardiovascular system, including on echocardiographic characteristics, is relevant.Aim. To study the prevalence of symptoms, cardiovascular disease and changes in echocardiographic data in persons after documented COVID-19 pneumonia 3 months after discharge from the hospital.Material and methods. The study included 106 patients after documented COVID-19 pneumonia. The patients underwent a comprehensive examination during hospitalization and 3 months±2 weeks after discharge from the hospital. The mean age of participants was 47±16 years (19-84 years); 49% of subjects were women.Results. Three months after hospital discharge, the symptoms persisted in 86% of examined patients. There were significant echocardiographic changes as follows: a decrease in LV end-diastolic, end-systolic and stroke volume (113,8±26,8 ml vs 93,5±29,4 ml; 37,7±13,0 ml vs 31,3±14,2 ml; 77,2±17,8 ml vs 62,2±18,7 ml, respectively, p<0,001 for all). The right ventricular anteroposterior dimension and the pulmonary trunk diameter decreased over time (26,0 [24,0-29,3] mm vs 25,0 [23,0-27,0] mm, p=0,004; 21,7±3,6 mm vs 18,7±2,5 mm, p<0,001), the same as the pulmonary artery systolic pressure, estimated by tricuspid regurgitation gradient (28,0 [25,0-32,25] mm Hg vs 21,5 [17,0-25,0] mm Hg). The right atrial volume (42,0 [37,0-50,0] m><0,001), the same as the pulmonary artery systolic pressure, estimated by tricuspid regurgitation gradient (28,0 [25,0-32,25] mm Hg vs 21,5 [17,0-25,0] mm Hg). The right atrial volume (42,0 [37,0-50,0] ml vs 31,0 [22,0-36,5] ml, p<0,001) a><0,001) and maximum width (36,1±4,6 mm vs 34,5±6,5 mm, p=0,023) decreased, while the right atrial maximum length increased (46,7±6,8 mm vs 48,6±7,1 mm, p=0,021).Conclusion. In survivors of COVID-19 pneumonia three months after hospital discharge, complaints persisted in 86% of cases. Cardiovascular diseases were detected in 52% of participants, including hypertension in 48,1% and coronary artery disease in 15,1%. Compared with in-hospital data, the echocardiographic characteristics improved, which was expressed mainly in a decrease in right heart load.https://russjcardiol.elpub.ru/jour/article/view/4656covid-19 pneumoniaechocardiographyright ventricleright atrium
spellingShingle D. V. Krinochkin
E. I. Yaroslavskaya
N. E. Shirokov
E. P. Gultyaeva
I. R. Krinochkina
I. O. Korovina
A. V. Mamarina
N. A. Osokina
N. N. Melnikov
T. A. Trifanova
E. A. Gorbatenko
T. I. Petelina
Cardiovascular status and echocardiographic changes in survivors of COVID-19 pneumonia three months after hospital discharge
Российский кардиологический журнал
covid-19 pneumonia
echocardiography
right ventricle
right atrium
title Cardiovascular status and echocardiographic changes in survivors of COVID-19 pneumonia three months after hospital discharge
title_full Cardiovascular status and echocardiographic changes in survivors of COVID-19 pneumonia three months after hospital discharge
title_fullStr Cardiovascular status and echocardiographic changes in survivors of COVID-19 pneumonia three months after hospital discharge
title_full_unstemmed Cardiovascular status and echocardiographic changes in survivors of COVID-19 pneumonia three months after hospital discharge
title_short Cardiovascular status and echocardiographic changes in survivors of COVID-19 pneumonia three months after hospital discharge
title_sort cardiovascular status and echocardiographic changes in survivors of covid 19 pneumonia three months after hospital discharge
topic covid-19 pneumonia
echocardiography
right ventricle
right atrium
url https://russjcardiol.elpub.ru/jour/article/view/4656
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