Immune mechanisms mediating the heterologous effects of BCG vaccination: a systematic review

Immune mechanisms mediating the heterologous effects of BCG vaccination: a systematic review

IntroductionBCG vaccination can have heterologous or non-specific effects (NSE) that confer resistance against pathogens other than its target Mycobacterium tuberculosis, but the underlying mechanisms are not fully understood.MethodsWe conducted a systematic review synthesising existing literature o...

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Bibliographic Details
Main Authors: Louis Torracinta, Nino Gogichadze, Rachel Tanner
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Immunology
Subjects:
BCG
heterologous effects of vaccination
trained immunity
T cells
humoral immunity
tuberculosis
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1567111/full
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