Effectiveness of endoscopic submucosal dissection in the management of internal hemorrhoids: a retrospective cohort study

Background: Improvement in internal hemorrhoids is frequently observed after endoscopic submucosal dissection (ESD) for rectal intraepithelial neoplasia. This study investigated the effectiveness of rectal ESD in the management of internal hemorrhoids. Objectives: Twenty-three patients who underwent...

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Main Authors: Hidenori Tanaka, Toshio Kuwai, Shinji Nagata, Naoki Asayama, Yuko Hiraga, Tomohiko Kohno, Yuzuru Tamaru, Masaki Kunihiro, Koki Nakamura, Ken Yamashita, Yoshihiro Kishida, Shiro Oka
Format: Article
Language:English
Published: SAGE Publishing 2025-07-01
Series:Therapeutic Advances in Gastroenterology
Online Access:https://doi.org/10.1177/17562848251355710
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author Hidenori Tanaka
Toshio Kuwai
Shinji Nagata
Naoki Asayama
Yuko Hiraga
Tomohiko Kohno
Yuzuru Tamaru
Masaki Kunihiro
Koki Nakamura
Ken Yamashita
Yoshihiro Kishida
Shiro Oka
author_facet Hidenori Tanaka
Toshio Kuwai
Shinji Nagata
Naoki Asayama
Yuko Hiraga
Tomohiko Kohno
Yuzuru Tamaru
Masaki Kunihiro
Koki Nakamura
Ken Yamashita
Yoshihiro Kishida
Shiro Oka
author_sort Hidenori Tanaka
collection DOAJ
description Background: Improvement in internal hemorrhoids is frequently observed after endoscopic submucosal dissection (ESD) for rectal intraepithelial neoplasia. This study investigated the effectiveness of rectal ESD in the management of internal hemorrhoids. Objectives: Twenty-three patients who underwent ESD for tumors adjacent to the dentate line and associated with internal hemorrhoids. Design: A single-arm, retrospective multi-center study. Methods: The focal improvement (at the scarring area after ESD) and complete improvement rates of hemorrhoids at follow-up colonoscopies were evaluated. Results: Most patients (87%) had mild hemorrhoids. The focal and complete improvement rates of hemorrhoids were 83% and 48%, respectively. Complete improvement rates were 75% (3/4), 42% (5/12), and 43% (3/7) for tumors involving ⩾1/2, between 1/4 and 1/2, and <1/4 of the circumference at the dentate line, respectively. No recurrence was observed after initial improvement, with a median observation period of 35 months. Conclusion: ESD may be an effective treatment for internal hemorrhoids.
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spelling doaj-art-e348e298cb7240ee94ca4939a1b09ad12025-08-20T03:28:51ZengSAGE PublishingTherapeutic Advances in Gastroenterology1756-28482025-07-011810.1177/17562848251355710Effectiveness of endoscopic submucosal dissection in the management of internal hemorrhoids: a retrospective cohort studyHidenori TanakaToshio KuwaiShinji NagataNaoki AsayamaYuko HiragaTomohiko KohnoYuzuru TamaruMasaki KunihiroKoki NakamuraKen YamashitaYoshihiro KishidaShiro OkaBackground: Improvement in internal hemorrhoids is frequently observed after endoscopic submucosal dissection (ESD) for rectal intraepithelial neoplasia. This study investigated the effectiveness of rectal ESD in the management of internal hemorrhoids. Objectives: Twenty-three patients who underwent ESD for tumors adjacent to the dentate line and associated with internal hemorrhoids. Design: A single-arm, retrospective multi-center study. Methods: The focal improvement (at the scarring area after ESD) and complete improvement rates of hemorrhoids at follow-up colonoscopies were evaluated. Results: Most patients (87%) had mild hemorrhoids. The focal and complete improvement rates of hemorrhoids were 83% and 48%, respectively. Complete improvement rates were 75% (3/4), 42% (5/12), and 43% (3/7) for tumors involving ⩾1/2, between 1/4 and 1/2, and <1/4 of the circumference at the dentate line, respectively. No recurrence was observed after initial improvement, with a median observation period of 35 months. Conclusion: ESD may be an effective treatment for internal hemorrhoids.https://doi.org/10.1177/17562848251355710
spellingShingle Hidenori Tanaka
Toshio Kuwai
Shinji Nagata
Naoki Asayama
Yuko Hiraga
Tomohiko Kohno
Yuzuru Tamaru
Masaki Kunihiro
Koki Nakamura
Ken Yamashita
Yoshihiro Kishida
Shiro Oka
Effectiveness of endoscopic submucosal dissection in the management of internal hemorrhoids: a retrospective cohort study
Therapeutic Advances in Gastroenterology
title Effectiveness of endoscopic submucosal dissection in the management of internal hemorrhoids: a retrospective cohort study
title_full Effectiveness of endoscopic submucosal dissection in the management of internal hemorrhoids: a retrospective cohort study
title_fullStr Effectiveness of endoscopic submucosal dissection in the management of internal hemorrhoids: a retrospective cohort study
title_full_unstemmed Effectiveness of endoscopic submucosal dissection in the management of internal hemorrhoids: a retrospective cohort study
title_short Effectiveness of endoscopic submucosal dissection in the management of internal hemorrhoids: a retrospective cohort study
title_sort effectiveness of endoscopic submucosal dissection in the management of internal hemorrhoids a retrospective cohort study
url https://doi.org/10.1177/17562848251355710
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