Modern strategies for the gastric cancer prevention

Gastric cancer (GC) is one of the top five cancer morbidity and mortality rates in the Russian Federation and worldwide. Currently, there is a decrease in gastric cancer incidence, which is associated with a decrease in the prevalence of Helicobacter pylori infection. However, due to changes in the...

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Main Authors: Dmitry S. Bordin, Karine A. Nikolskaya, Margarita V. Chebotareva, Igor E. Khatkov
Format: Article
Language:Russian
Published: "Consilium Medicum" Publishing house 2024-12-01
Series:Терапевтический архив
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Online Access:https://ter-arkhiv.ru/0040-3660/article/viewFile/637439/pdf
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author Dmitry S. Bordin
Karine A. Nikolskaya
Margarita V. Chebotareva
Igor E. Khatkov
author_facet Dmitry S. Bordin
Karine A. Nikolskaya
Margarita V. Chebotareva
Igor E. Khatkov
author_sort Dmitry S. Bordin
collection DOAJ
description Gastric cancer (GC) is one of the top five cancer morbidity and mortality rates in the Russian Federation and worldwide. Currently, there is a decrease in gastric cancer incidence, which is associated with a decrease in the prevalence of Helicobacter pylori infection. However, due to changes in the population structure and increased life expectancy, the absolute number of gastric cancer cases and mortality are expected to increase. GC is a consequence of long-term chronic gastritis. At least 90% of gastric cancers are caused by H. pylori. Reducing the incidence and mortality from GC is achievable with a reasonable combination of 2 strategies: primary prevention based on the detection and eradication of H. pylori, and secondary prevention, which is based on endoscopic screening of early GC and the formation of high-risk groups for cancer development and their subsequent endoscopic observation.
format Article
id doaj-art-e32810dc7cea4a6cabb812ea7e4a43b9
institution DOAJ
issn 0040-3660
2309-5342
language Russian
publishDate 2024-12-01
publisher "Consilium Medicum" Publishing house
record_format Article
series Терапевтический архив
spelling doaj-art-e32810dc7cea4a6cabb812ea7e4a43b92025-08-20T03:01:07Zrus"Consilium Medicum" Publishing houseТерапевтический архив0040-36602309-53422024-12-0196121115112010.26442/00403660.2024.12.20308078634Modern strategies for the gastric cancer preventionDmitry S. Bordin0https://orcid.org/0000-0003-2815-3992Karine A. Nikolskaya1https://orcid.org/0000-0002-1477-888XMargarita V. Chebotareva2https://orcid.org/0000-0002-0175-4328Igor E. Khatkov3Loginov Moscow Clinical Scientific CenterLoginov Moscow Clinical Scientific CenterLoginov Moscow Clinical Scientific CenterLoginov Moscow Clinical Scientific CenterGastric cancer (GC) is one of the top five cancer morbidity and mortality rates in the Russian Federation and worldwide. Currently, there is a decrease in gastric cancer incidence, which is associated with a decrease in the prevalence of Helicobacter pylori infection. However, due to changes in the population structure and increased life expectancy, the absolute number of gastric cancer cases and mortality are expected to increase. GC is a consequence of long-term chronic gastritis. At least 90% of gastric cancers are caused by H. pylori. Reducing the incidence and mortality from GC is achievable with a reasonable combination of 2 strategies: primary prevention based on the detection and eradication of H. pylori, and secondary prevention, which is based on endoscopic screening of early GC and the formation of high-risk groups for cancer development and their subsequent endoscopic observation.https://ter-arkhiv.ru/0040-3660/article/viewFile/637439/pdfgastric cancerprimary prevention of gastric cancerhelicobacter pyloriendoscopic screening
spellingShingle Dmitry S. Bordin
Karine A. Nikolskaya
Margarita V. Chebotareva
Igor E. Khatkov
Modern strategies for the gastric cancer prevention
Терапевтический архив
gastric cancer
primary prevention of gastric cancer
helicobacter pylori
endoscopic screening
title Modern strategies for the gastric cancer prevention
title_full Modern strategies for the gastric cancer prevention
title_fullStr Modern strategies for the gastric cancer prevention
title_full_unstemmed Modern strategies for the gastric cancer prevention
title_short Modern strategies for the gastric cancer prevention
title_sort modern strategies for the gastric cancer prevention
topic gastric cancer
primary prevention of gastric cancer
helicobacter pylori
endoscopic screening
url https://ter-arkhiv.ru/0040-3660/article/viewFile/637439/pdf
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AT karineanikolskaya modernstrategiesforthegastriccancerprevention
AT margaritavchebotareva modernstrategiesforthegastriccancerprevention
AT igorekhatkov modernstrategiesforthegastriccancerprevention