Clinical, pharmacology and in vivo studies of QingDai (indigo naturalis) promotes mucosal healing and symptom improvement in ulcerative colitis by regulating the AHR-Th17/Treg pathway

Clinical, pharmacology and in vivo studies of QingDai (indigo naturalis) promotes mucosal healing and symptom improvement in ulcerative colitis by regulating the AHR-Th17/Treg pathway

Abstract Qingdai (QD), derived from various plant sources, is commonly used in traditional Chinese medicine for ulcerative colitis (UC) treatment. However, the clinical efficacy and mechanisms of orally administered QD remain unclear. This study aims to evaluate QD’s efficacy in UC treatment and unc...

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Bibliographic Details
Main Authors: Sizhen Gu, Yan Xue, Xiaowen Liu, Yini Tang, Dong Wang, Dongmei Wu, Mingrong Yao, Zehua Xia, Sen Yang, Gan Cai, Shigui Xue, Danbo Dou
Format: Article
Language:English
Published: BMC 2024-11-01
Series:Journal of Inflammation
Subjects:
Ulcerative Colitis
Qingdai
Clinical efficacy
UPLC-Q-TOF-MS
AHR
Th17/Treg
Online Access:https://doi.org/10.1186/s12950-024-00413-x
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