Coexistence of bla NDM-1, mcr-1 and bla CTX-M-199 in an ST499 multidrug resistant Klebsiella pneumoniae Isolate

Coexistence of bla NDM-1, mcr-1 and bla CTX-M-199 in an ST499 multidrug resistant Klebsiella pneumoniae Isolate

Abstract The coexistence of multiple resistance genes within a single bacterial strain presents a significant public health challenge, as it complicates treatment options and accelerates the spread of multidrug resistance. While the co-occurrence of bla NDM-1 and mcr-1 genes in Klebsiella pneumoniae...

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Bibliographic Details
Main Authors: Xinjun Hu, Bingyou Yin, Ruishan Liu, Lu Gong, Xiaolu Yang, Zhenghao Lou, Haowei Ye, Bingyang Shang, Yibing Shang, Yingjian Zhang
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Scientific Reports
Subjects:
Klebsiella pneumoniae
Multidrug resistance
MCR-1
bla NDM-1
bla CTX-M-199
Whole genome sequencing
Online Access:https://doi.org/10.1038/s41598-025-03759-1
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