Serum Albumin Concentration and the Risk of Cardiovascular Disease and Acute Coronary Syndrome — a Narrative Review

Cardiovascular diseases are the primary cause of global health decline. Conditions that cause inflammation and excessive oxidation are present in the early development of the majority of cardiovascular diseases, including coronary artery disease and heart failure. Among the many physiological functi...

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Main Authors: Czinege Maria, Ruța Florina, Nyulas Victoria, Halațiu Vasile-Bogdan, Nyulas Tiberiu, Benedek Theodora
Format: Article
Language:English
Published: Sciendo 2025-03-01
Series:Journal of Cardiovascular Emergencies
Subjects:
Online Access:https://doi.org/10.2478/jce-2024-0024
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author Czinege Maria
Ruța Florina
Nyulas Victoria
Halațiu Vasile-Bogdan
Nyulas Tiberiu
Benedek Theodora
author_facet Czinege Maria
Ruța Florina
Nyulas Victoria
Halațiu Vasile-Bogdan
Nyulas Tiberiu
Benedek Theodora
author_sort Czinege Maria
collection DOAJ
description Cardiovascular diseases are the primary cause of global health decline. Conditions that cause inflammation and excessive oxidation are present in the early development of the majority of cardiovascular diseases, including coronary artery disease and heart failure. Among the many physiological functions of albumin, its antioxidant, anti-inflammatory, anticoagulant, and antiaggregant properties are the most important. Low serum albumin levels are associated with the occurrence of various cardiovascular diseases such as coronary artery disease, stroke, heart failure, and atrial fibrillation. Several recent meta-analyses support the idea that hypoalbuminemia may act as a modifiable risk factor that increases oxidative stress and inflammation, contributing to the development and progression of cardiovascular diseases. However, it is unclear whether correcting hypoalbuminemia can improve outcomes for patients with cardiovascular diseases and reduce mortality rates. In this regard, further research is crucial.
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id doaj-art-e319bbad7baf42f4a36d8dc3a9a34544
institution OA Journals
issn 2457-5518
language English
publishDate 2025-03-01
publisher Sciendo
record_format Article
series Journal of Cardiovascular Emergencies
spelling doaj-art-e319bbad7baf42f4a36d8dc3a9a345442025-08-20T01:54:15ZengSciendoJournal of Cardiovascular Emergencies2457-55182025-03-01111111910.2478/jce-2024-0024Serum Albumin Concentration and the Risk of Cardiovascular Disease and Acute Coronary Syndrome — a Narrative ReviewCzinege Maria0Ruța Florina1Nyulas Victoria2Halațiu Vasile-Bogdan3Nyulas Tiberiu4Benedek Theodora5Department of Doctoral School, George Emil Palade University of Medicine, Pharmacy, Science and Technology, Târgu Mureș, RomaniaDepartment of Community Nutrition and Food Hygiene, George Emil Palade University of Medicine, Pharmacy, Science and Technology, Târgu Mureș, RomaniaDepartment of Informatics and Medical Biostatistics, George Emil Palade University of Medicine, Pharmacy, Science and Technology, Târgu Mureș, RomaniaDepartment of Physiology, George Emil Palade University of Medicine, Pharmacy, Science and Technology, Târgu Mureș, RomaniaDepartment of Physiology, George Emil Palade University of Medicine, Pharmacy, Science and Technology, Târgu Mureș, RomaniaDepartment of Cardiology, George Emil Palade University of Medicine, Pharmacy, Science and Technology, Târgu Mureș, RomaniaCardiovascular diseases are the primary cause of global health decline. Conditions that cause inflammation and excessive oxidation are present in the early development of the majority of cardiovascular diseases, including coronary artery disease and heart failure. Among the many physiological functions of albumin, its antioxidant, anti-inflammatory, anticoagulant, and antiaggregant properties are the most important. Low serum albumin levels are associated with the occurrence of various cardiovascular diseases such as coronary artery disease, stroke, heart failure, and atrial fibrillation. Several recent meta-analyses support the idea that hypoalbuminemia may act as a modifiable risk factor that increases oxidative stress and inflammation, contributing to the development and progression of cardiovascular diseases. However, it is unclear whether correcting hypoalbuminemia can improve outcomes for patients with cardiovascular diseases and reduce mortality rates. In this regard, further research is crucial.https://doi.org/10.2478/jce-2024-0024acute coronary syndromeserum albuminprognosisinflammation
spellingShingle Czinege Maria
Ruța Florina
Nyulas Victoria
Halațiu Vasile-Bogdan
Nyulas Tiberiu
Benedek Theodora
Serum Albumin Concentration and the Risk of Cardiovascular Disease and Acute Coronary Syndrome — a Narrative Review
Journal of Cardiovascular Emergencies
acute coronary syndrome
serum albumin
prognosis
inflammation
title Serum Albumin Concentration and the Risk of Cardiovascular Disease and Acute Coronary Syndrome — a Narrative Review
title_full Serum Albumin Concentration and the Risk of Cardiovascular Disease and Acute Coronary Syndrome — a Narrative Review
title_fullStr Serum Albumin Concentration and the Risk of Cardiovascular Disease and Acute Coronary Syndrome — a Narrative Review
title_full_unstemmed Serum Albumin Concentration and the Risk of Cardiovascular Disease and Acute Coronary Syndrome — a Narrative Review
title_short Serum Albumin Concentration and the Risk of Cardiovascular Disease and Acute Coronary Syndrome — a Narrative Review
title_sort serum albumin concentration and the risk of cardiovascular disease and acute coronary syndrome a narrative review
topic acute coronary syndrome
serum albumin
prognosis
inflammation
url https://doi.org/10.2478/jce-2024-0024
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