A comparison of anatomic and cellular transcriptome structures across 40 human brain diseases.

Genes associated with risk for brain disease exhibit characteristic expression patterns that reflect both anatomical and cell type relationships. Brain-wide transcriptomic patterns of disease risk genes provide a molecular-based signature, based on differential co-expression, that is often unique to...

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Bibliographic Details
Main Authors: Yashar Zeighami, Trygve E Bakken, Thomas Nickl-Jockschat, Zeru Peterson, Anil G Jegga, Jeremy A Miller, Jay Schulkin, Alan C Evans, Ed S Lein, Michael Hawrylycz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-04-01
Series:PLoS Biology
Online Access:https://journals.plos.org/plosbiology/article/file?id=10.1371/journal.pbio.3002058&type=printable
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