A Review Leveraging a Rare and Unusual Case of Basal Cell Carcinoma of the Prostate
Basal cell carcinoma (BCC) is a rare nonacinar variant of prostatic carcinoma. In spite of prostatic acinar adenocarcinoma being one of the most common carcinomas in prostate, <100 prostatic BCC cases have been reported to date. Adenoid cystic/cribriform histology has been described in varying pr...
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| Format: | Article |
| Language: | English |
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Wiley
2021-01-01
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| Series: | Case Reports in Pathology |
| Online Access: | http://dx.doi.org/10.1155/2021/5520581 |
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| _version_ | 1832550525083582464 |
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| author | Lin He Christopher Metter Vitaly Margulis Payal Kapur |
| author_facet | Lin He Christopher Metter Vitaly Margulis Payal Kapur |
| author_sort | Lin He |
| collection | DOAJ |
| description | Basal cell carcinoma (BCC) is a rare nonacinar variant of prostatic carcinoma. In spite of prostatic acinar adenocarcinoma being one of the most common carcinomas in prostate, <100 prostatic BCC cases have been reported to date. Adenoid cystic/cribriform histology has been described in varying proportions to occur in prostatic BCC and is reported to be associated with aggressive behavior and high risk of metastasis. Herein, we present a case of prostatic BCC with adenoid cystic morphology, comprehensively describe its immunohistochemical and MYB/MYBL1 gene rearrangement findings, discuss its differential diagnosis, and review the literature of this rare entity. |
| format | Article |
| id | doaj-art-e3143c64eebd49008421143498161073 |
| institution | Kabale University |
| issn | 2090-6781 2090-679X |
| language | English |
| publishDate | 2021-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Pathology |
| spelling | doaj-art-e3143c64eebd490084211434981610732025-02-03T06:06:31ZengWileyCase Reports in Pathology2090-67812090-679X2021-01-01202110.1155/2021/55205815520581A Review Leveraging a Rare and Unusual Case of Basal Cell Carcinoma of the ProstateLin He0Christopher Metter1Vitaly Margulis2Payal Kapur3Department of Pathology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USADepartment of Pathology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USADepartment of Urology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USADepartment of Pathology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USABasal cell carcinoma (BCC) is a rare nonacinar variant of prostatic carcinoma. In spite of prostatic acinar adenocarcinoma being one of the most common carcinomas in prostate, <100 prostatic BCC cases have been reported to date. Adenoid cystic/cribriform histology has been described in varying proportions to occur in prostatic BCC and is reported to be associated with aggressive behavior and high risk of metastasis. Herein, we present a case of prostatic BCC with adenoid cystic morphology, comprehensively describe its immunohistochemical and MYB/MYBL1 gene rearrangement findings, discuss its differential diagnosis, and review the literature of this rare entity.http://dx.doi.org/10.1155/2021/5520581 |
| spellingShingle | Lin He Christopher Metter Vitaly Margulis Payal Kapur A Review Leveraging a Rare and Unusual Case of Basal Cell Carcinoma of the Prostate Case Reports in Pathology |
| title | A Review Leveraging a Rare and Unusual Case of Basal Cell Carcinoma of the Prostate |
| title_full | A Review Leveraging a Rare and Unusual Case of Basal Cell Carcinoma of the Prostate |
| title_fullStr | A Review Leveraging a Rare and Unusual Case of Basal Cell Carcinoma of the Prostate |
| title_full_unstemmed | A Review Leveraging a Rare and Unusual Case of Basal Cell Carcinoma of the Prostate |
| title_short | A Review Leveraging a Rare and Unusual Case of Basal Cell Carcinoma of the Prostate |
| title_sort | review leveraging a rare and unusual case of basal cell carcinoma of the prostate |
| url | http://dx.doi.org/10.1155/2021/5520581 |
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