A retrospective study on colorectal lesion risk assessment in patients with early oesophagogastric cancer
Abstract An increasing number of patients with oesophageal or gastric cancer are being diagnosed with colorectal lesions. This single-centre, retrospective study assessed the risk of colorectal lesions in patients with early oesophagogastric cancer. 170 patients were enrolled in the early oesophagog...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-07-01
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| Series: | npj Gut and Liver |
| Online Access: | https://doi.org/10.1038/s44355-025-00026-y |
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| Summary: | Abstract An increasing number of patients with oesophageal or gastric cancer are being diagnosed with colorectal lesions. This single-centre, retrospective study assessed the risk of colorectal lesions in patients with early oesophagogastric cancer. 170 patients were enrolled in the early oesophagogastric cancer group, of whom 113 (66.47%) had colorectal lesions. 238 individuals were included in the control group, among whom 38 (15.97%) were diagnosed with colorectal lesions. The incidence of colorectal lesions between the two groups was statistically significant (P < 0.05), and patients with early oesophagogastric cancer had a risk of colorectal lesions (odds ratio = 10.434, 95% confidence interval = 6.516–16.708). Multivariate analysis identified three independent risk factors: faecal occult blood test positivity, oesophagogastric lesion diameter >2 cm, and the presence of multiple oesophagogastric lesions. These findings suggest that the early oesophagogastric cancer increased the risk of colorectal lesions, particularly among individuals with the identified risk factors. |
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| ISSN: | 3004-9806 |