CD36 as a marker of acute myeloid leukemia prognosis: A systematic review
CD36 is a glycoprotein associated with resistance to chemotherapy and the recurrence of acute myeloid leukemia. This systematic review aims to evaluate the impact of CD36 on the prognosis of acute myeloid leukemia, a complex heterogeneous malignant hematopoietic disease. The Embase, Scopus, Web of S...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-07-01
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| Series: | Hematology, Transfusion and Cell Therapy |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2531137925001294 |
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| author | Marina Chaves Amantéa Rafaela Pires da Silva Larissa Ranini Soares João Lorenzo de Medeiros Pereira Ana Paula Duarte de Souza |
| author_facet | Marina Chaves Amantéa Rafaela Pires da Silva Larissa Ranini Soares João Lorenzo de Medeiros Pereira Ana Paula Duarte de Souza |
| author_sort | Marina Chaves Amantéa |
| collection | DOAJ |
| description | CD36 is a glycoprotein associated with resistance to chemotherapy and the recurrence of acute myeloid leukemia. This systematic review aims to evaluate the impact of CD36 on the prognosis of acute myeloid leukemia, a complex heterogeneous malignant hematopoietic disease. The Embase, Scopus, Web of Science, Cochrane Library and SciELO databases were searched until September 2023. Only studies that analyzed CD36 expression in humans were included. Of 905 articles identified from the databases, 600 were screened and nine were included. The Newcastle-Ottawa Scale was used to evaluate the methodological quality of the studies. According to this systematic review, CD36 is associated with different prognostic factors in acute myeloid leukemia, including remission and relapse of the disease, overall survival, and chemoresistance. |
| format | Article |
| id | doaj-art-e30f11ddb7304a7dbcd829ef88ad4b92 |
| institution | Kabale University |
| issn | 2531-1379 |
| language | English |
| publishDate | 2025-07-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Hematology, Transfusion and Cell Therapy |
| spelling | doaj-art-e30f11ddb7304a7dbcd829ef88ad4b922025-08-20T03:41:26ZengElsevierHematology, Transfusion and Cell Therapy2531-13792025-07-0147310386110.1016/j.htct.2025.103861CD36 as a marker of acute myeloid leukemia prognosis: A systematic reviewMarina Chaves Amantéa0Rafaela Pires da Silva1Larissa Ranini Soares2João Lorenzo de Medeiros Pereira3Ana Paula Duarte de Souza4Escola de Ciências da Saúde e da Vida, Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS), Porto Alegre, RS, BrazilEscola de Ciências da Saúde e da Vida, Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS), Porto Alegre, RS, BrazilEscola de Ciências da Saúde e da Vida, Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS), Porto Alegre, RS, BrazilEscola de Ciências da Saúde e da Vida, Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS), Porto Alegre, RS, BrazilCorresponding author. Laboratory of Clinical and Experimental Immunology, Health and Life Science School, Pontifical Catholic University of Rio Grande do Sul – Av. Ipiranga, 6681, CEP 90619-900, Porto Alegre, RS, Brazil.; Escola de Ciências da Saúde e da Vida, Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS), Porto Alegre, RS, BrazilCD36 is a glycoprotein associated with resistance to chemotherapy and the recurrence of acute myeloid leukemia. This systematic review aims to evaluate the impact of CD36 on the prognosis of acute myeloid leukemia, a complex heterogeneous malignant hematopoietic disease. The Embase, Scopus, Web of Science, Cochrane Library and SciELO databases were searched until September 2023. Only studies that analyzed CD36 expression in humans were included. Of 905 articles identified from the databases, 600 were screened and nine were included. The Newcastle-Ottawa Scale was used to evaluate the methodological quality of the studies. According to this systematic review, CD36 is associated with different prognostic factors in acute myeloid leukemia, including remission and relapse of the disease, overall survival, and chemoresistance.http://www.sciencedirect.com/science/article/pii/S2531137925001294Acute myeloid leukemiaAntigenCd36PrognosisPrognostic factors |
| spellingShingle | Marina Chaves Amantéa Rafaela Pires da Silva Larissa Ranini Soares João Lorenzo de Medeiros Pereira Ana Paula Duarte de Souza CD36 as a marker of acute myeloid leukemia prognosis: A systematic review Hematology, Transfusion and Cell Therapy Acute myeloid leukemia Antigen Cd36 Prognosis Prognostic factors |
| title | CD36 as a marker of acute myeloid leukemia prognosis: A systematic review |
| title_full | CD36 as a marker of acute myeloid leukemia prognosis: A systematic review |
| title_fullStr | CD36 as a marker of acute myeloid leukemia prognosis: A systematic review |
| title_full_unstemmed | CD36 as a marker of acute myeloid leukemia prognosis: A systematic review |
| title_short | CD36 as a marker of acute myeloid leukemia prognosis: A systematic review |
| title_sort | cd36 as a marker of acute myeloid leukemia prognosis a systematic review |
| topic | Acute myeloid leukemia Antigen Cd36 Prognosis Prognostic factors |
| url | http://www.sciencedirect.com/science/article/pii/S2531137925001294 |
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