Viral RNA polymerase as a SUMOylation decoy inhibits RNA quality control to promote potyvirus infection

Viral RNA polymerase as a SUMOylation decoy inhibits RNA quality control to promote potyvirus infection

Abstract Potyvirids are the largest group of plant RNA viruses. Pelota, a core component of RNA quality controls (RQC), promotes the degradation of potyvirids’ genomic RNA by recognizing a specific G1-2A6-7 motif. Here we demonstrate that the viral RNA-dependent RNA polymerase, NIb, acts as a SUMOyl...

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Bibliographic Details
Main Authors: Linhao Ge, Mingxuan Jia, Hongying Shan, Weifang Gao, Lu Jiang, Hongguang Cui, Xiaofei Cheng, Marilyne Uzest, Xueping Zhou, Aiming Wang, Fangfang Li
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-55288-6
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