The Effects of the Incorporation of Nano-Hydroxyapatite on Physico-Chemical Properties of Calcium-Enriched Mixed Cement

Background: Calcium-enriched mixed (CEM) cement, though beneficial in endodontic applications, requires improvements in its physico-chemical properties to enhance clinical outcomes.Purpose: This study was conceptualized to investigate the impact of incorporating nano-hydroxyapatite (nHAP) on the phy...

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Main Authors: Mohammadreza Nabavizadeh, Yasser Samadi, Safoora Sahebi, Fateme Eskandari
Format: Article
Language:English
Published: Shiraz University of Medical Sciences 2025-06-01
Series:Journal of Dentistry
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Online Access:https://dentjods.sums.ac.ir/article_50564_4daa12de62488e075af7d5c2cba2fc5b.pdf
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author Mohammadreza Nabavizadeh
Yasser Samadi
Safoora Sahebi
Fateme Eskandari
author_facet Mohammadreza Nabavizadeh
Yasser Samadi
Safoora Sahebi
Fateme Eskandari
author_sort Mohammadreza Nabavizadeh
collection DOAJ
description Background: Calcium-enriched mixed (CEM) cement, though beneficial in endodontic applications, requires improvements in its physico-chemical properties to enhance clinical outcomes.Purpose: This study was conceptualized to investigate the impact of incorporating nano-hydroxyapatite (nHAP) on the physico-chemical properties of CEM cement.Materials and Method: In this experimental study, nHAP powder at 5 and 10 wt% ratio was thoroughly mixed with CEM cement powder. Then they were mixed with a ratio of 1 g of powder to 0.33g of liquid and placed in special molds for each test. CEM cement without nHAP was used as a control sample. Samples were assessed for setting time, compressive strength, solubility, and pH.Results: According to our results, the addition of 5% nHAP significantly increased the initial setting time (S1) and compressive strength after 24 hours, while the addition of 5% and 10% nHAP significantly enhanced the pH of the CEM cement.Conclusion: Incorporation of 5% nHAP to CEM cement, although delayed S1 of this cement, but increased the pH level of CEM cement, which in turn could potentially improve the antimicrobial properties of CEM cement. Furthermore, the addition of 5% nHAP to CEM cement notably improved the compressive strength in the short term, which can be beneficial in withstanding the chewing forces after applying the cement in the oral environment. It is recommended to select an appropriate concentration of nHAP to optimize the properties of CEM cement based on the findings of this study.
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spelling doaj-art-e3079056ce1b46a1a0d305b6bfde1ffd2025-08-20T03:22:26ZengShiraz University of Medical SciencesJournal of Dentistry2345-64852345-64182025-06-0126217718510.30476/dentjods.2024.101837.231950564The Effects of the Incorporation of Nano-Hydroxyapatite on Physico-Chemical Properties of Calcium-Enriched Mixed CementMohammadreza Nabavizadeh0Yasser Samadi1Safoora Sahebi2Fateme Eskandari3Oral and Dental Disease Research Center, Dept. of Endodontics, School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Fars, Iran.Dept. of Endodontics, Oral Health Center, Health Research Institute, School of Dentistry, Babol University of Medical Sciences, Babol, Iran.Dept. of Endodontics, School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Fars, Iran.Dentist, School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Iran.Background: Calcium-enriched mixed (CEM) cement, though beneficial in endodontic applications, requires improvements in its physico-chemical properties to enhance clinical outcomes.Purpose: This study was conceptualized to investigate the impact of incorporating nano-hydroxyapatite (nHAP) on the physico-chemical properties of CEM cement.Materials and Method: In this experimental study, nHAP powder at 5 and 10 wt% ratio was thoroughly mixed with CEM cement powder. Then they were mixed with a ratio of 1 g of powder to 0.33g of liquid and placed in special molds for each test. CEM cement without nHAP was used as a control sample. Samples were assessed for setting time, compressive strength, solubility, and pH.Results: According to our results, the addition of 5% nHAP significantly increased the initial setting time (S1) and compressive strength after 24 hours, while the addition of 5% and 10% nHAP significantly enhanced the pH of the CEM cement.Conclusion: Incorporation of 5% nHAP to CEM cement, although delayed S1 of this cement, but increased the pH level of CEM cement, which in turn could potentially improve the antimicrobial properties of CEM cement. Furthermore, the addition of 5% nHAP to CEM cement notably improved the compressive strength in the short term, which can be beneficial in withstanding the chewing forces after applying the cement in the oral environment. It is recommended to select an appropriate concentration of nHAP to optimize the properties of CEM cement based on the findings of this study.https://dentjods.sums.ac.ir/article_50564_4daa12de62488e075af7d5c2cba2fc5b.pdfsolubilitycompressive strengthphcalcium silicatenanoparticles
spellingShingle Mohammadreza Nabavizadeh
Yasser Samadi
Safoora Sahebi
Fateme Eskandari
The Effects of the Incorporation of Nano-Hydroxyapatite on Physico-Chemical Properties of Calcium-Enriched Mixed Cement
Journal of Dentistry
solubility
compressive strength
ph
calcium silicate
nanoparticles
title The Effects of the Incorporation of Nano-Hydroxyapatite on Physico-Chemical Properties of Calcium-Enriched Mixed Cement
title_full The Effects of the Incorporation of Nano-Hydroxyapatite on Physico-Chemical Properties of Calcium-Enriched Mixed Cement
title_fullStr The Effects of the Incorporation of Nano-Hydroxyapatite on Physico-Chemical Properties of Calcium-Enriched Mixed Cement
title_full_unstemmed The Effects of the Incorporation of Nano-Hydroxyapatite on Physico-Chemical Properties of Calcium-Enriched Mixed Cement
title_short The Effects of the Incorporation of Nano-Hydroxyapatite on Physico-Chemical Properties of Calcium-Enriched Mixed Cement
title_sort effects of the incorporation of nano hydroxyapatite on physico chemical properties of calcium enriched mixed cement
topic solubility
compressive strength
ph
calcium silicate
nanoparticles
url https://dentjods.sums.ac.ir/article_50564_4daa12de62488e075af7d5c2cba2fc5b.pdf
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