Discrepancies between human and murine model cerebral aneurysms at single-cell resolution

Discrepancies between human and murine model cerebral aneurysms at single-cell resolution

BackgroundThe murine model of cerebral aneurysm (CA) serves as a prevalent tool for investigating the molecular underpinnings of CA. However, the extent to which the CA murine model aligns with that of human remains elusive.MethodsThe present study employed a comprehensive integration and exploratio...

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Bibliographic Details
Main Authors: Hang Ji, Guicheng Kuang, Hailan Yang, Haitao Liu, Yue Li, Shaoshan Hu, Anqi Xiao, Chao You, Haogeng Sun, Chaofeng Fan, Guozhang Sun
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-03-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
cerebral aneurysm
human CA
murine model CA
single-cell RNA sequencing
inflammation
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2025.1512938/full
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