Antiviral immunity within neural stem cells distinguishes Enterovirus-D68 strain differences in forebrain organoids
Abstract Neural stem cells have intact innate immune responses that protect them from virus infection and cell death. Yet, viruses can antagonize such responses to establish neuropathogenesis. Using a forebrain organoid model system at two developmental time points, we identified that neural stem ce...
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| Main Authors: | Christine Vazquez, Seble G. Negatu, Carl D. Bannerman, Sowmya Sriram, Guo-Li Ming, Kellie A. Jurado |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2024-11-01
|
| Series: | Journal of Neuroinflammation |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12974-024-03275-5 |
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