Clozapine for Quetiapine-Refractory Psychosis in Parkinson’s Disease: A Long-Term Single-Center Retrospective Study

Conclusions: Clozapine is often effective in the treatment of psychotic disorders in PD including PDPsy poorly or only transiently responding to quetiapine. Side effects including agranulocytosis are manageable in the majority of cases. Clozapine treatment should not be delayed if other measures aga...

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Main Author: Walter Pirker
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:Parkinson's Disease
Online Access:http://dx.doi.org/10.1155/padi/1068722
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author Walter Pirker
author_facet Walter Pirker
author_sort Walter Pirker
collection DOAJ
description Conclusions: Clozapine is often effective in the treatment of psychotic disorders in PD including PDPsy poorly or only transiently responding to quetiapine. Side effects including agranulocytosis are manageable in the majority of cases. Clozapine treatment should not be delayed if other measures against PDPsy prove ineffective.
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spelling doaj-art-e300ddc2afd8401d8aa007cf84e1eb492025-08-20T02:09:34ZengWileyParkinson's Disease2042-00802025-01-01202510.1155/padi/1068722Clozapine for Quetiapine-Refractory Psychosis in Parkinson’s Disease: A Long-Term Single-Center Retrospective StudyWalter Pirker0Department of NeurologyConclusions: Clozapine is often effective in the treatment of psychotic disorders in PD including PDPsy poorly or only transiently responding to quetiapine. Side effects including agranulocytosis are manageable in the majority of cases. Clozapine treatment should not be delayed if other measures against PDPsy prove ineffective.http://dx.doi.org/10.1155/padi/1068722
spellingShingle Walter Pirker
Clozapine for Quetiapine-Refractory Psychosis in Parkinson’s Disease: A Long-Term Single-Center Retrospective Study
Parkinson's Disease
title Clozapine for Quetiapine-Refractory Psychosis in Parkinson’s Disease: A Long-Term Single-Center Retrospective Study
title_full Clozapine for Quetiapine-Refractory Psychosis in Parkinson’s Disease: A Long-Term Single-Center Retrospective Study
title_fullStr Clozapine for Quetiapine-Refractory Psychosis in Parkinson’s Disease: A Long-Term Single-Center Retrospective Study
title_full_unstemmed Clozapine for Quetiapine-Refractory Psychosis in Parkinson’s Disease: A Long-Term Single-Center Retrospective Study
title_short Clozapine for Quetiapine-Refractory Psychosis in Parkinson’s Disease: A Long-Term Single-Center Retrospective Study
title_sort clozapine for quetiapine refractory psychosis in parkinson s disease a long term single center retrospective study
url http://dx.doi.org/10.1155/padi/1068722
work_keys_str_mv AT walterpirker clozapineforquetiapinerefractorypsychosisinparkinsonsdiseasealongtermsinglecenterretrospectivestudy