Impairment of neuronal activity in the dorsolateral prefrontal cortex occurs early in parkinsonism

Impairment of neuronal activity in the dorsolateral prefrontal cortex occurs early in parkinsonism

BackgroundParkinson’s disease (PD) is often characterized by altered rates and patterns of neuronal activity in the sensorimotor regions of the basal ganglia thalamocortical network. Little is known, however, regarding how neuronal activity in the executive control network of the brain changes in th...

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Bibliographic Details
Main Authors: Noah Hjelle, Biswaranjan Mohanty, Tanner Hubbard, Matthew D. Johnson, Jing Wang, Luke A. Johnson, Jerrold L. Vitek
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Neuroscience
Subjects:
Parkinson’s disease
rhesus macaque
dorsolateral prefrontal cortex
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MPTP
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2025.1521443/full
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