Single-nucleus RNA sequencing reveals a preclinical model for the most common subtype of glioblastoma

Single-nucleus RNA sequencing reveals a preclinical model for the most common subtype of glioblastoma

Abstract Different glioblastoma (GBM) subtypes have been identified based on the tumor microenvironment (TME). The discovery of new therapies for these hard-to-treat tumors requires a thorough characterization of preclinical models, including their TME, to apply preclinical results to the most simil...

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Main Authors: Laura García-Vicente, María Martínez-Fernández, Michael Borja, Vanessa Tran, Andrea Álvarez-Vázquez, Raquel Flores-Hernández, Yuxin Ding, Raúl González-Sánchez, Alejandro Granados, Erin McGeever, Yang-Joon Kim, Angela Detweiler, Honey Mekonen, Sheryl Paul, Angela O. Pisco, Norma F. Neff, Arantxa Tabernero
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-025-08092-x
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