Anaplastic Large Cell Lymphoma Occurring in an HIV-Positive Patient
Cases of anaplastic large-cell lymphoma (ALCL) of T phenotype are sparse in the setting of HIV patients. We report herein a case of T-ALCL, with an advanced stage, pulmonary involvement, high HIV viral load, and low CD4 level. Anaplastic lymphoma kinase (ALK) protein expression was negative. Anthrac...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | Case Reports in Hematology |
| Online Access: | http://dx.doi.org/10.1155/2012/180204 |
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| _version_ | 1832553364393558016 |
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| author | Philippe Genet Driss Chaoui Virginie Masse Ahmad Al Jijakli Nina Arakelyan Laurent Sutton |
| author_facet | Philippe Genet Driss Chaoui Virginie Masse Ahmad Al Jijakli Nina Arakelyan Laurent Sutton |
| author_sort | Philippe Genet |
| collection | DOAJ |
| description | Cases of anaplastic large-cell lymphoma (ALCL) of T phenotype are sparse in the setting of HIV patients. We report herein a case of T-ALCL, with an advanced stage, pulmonary involvement, high HIV viral load, and low CD4 level. Anaplastic lymphoma kinase (ALK) protein expression was negative. Anthracyclin-based chemotherapy was unsuccessful. The literature review was performed focusing on incidence, clinical characteristics, prognosis, and physiopathology of ALCL in HIV patients. More data are needed to improve the knowledge of such cases and to define a better treatment approach. |
| format | Article |
| id | doaj-art-e2f5dd81143e4ecbb526ba132d609b35 |
| institution | Kabale University |
| issn | 2090-6560 2090-6579 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Hematology |
| spelling | doaj-art-e2f5dd81143e4ecbb526ba132d609b352025-02-03T05:54:10ZengWileyCase Reports in Hematology2090-65602090-65792012-01-01201210.1155/2012/180204180204Anaplastic Large Cell Lymphoma Occurring in an HIV-Positive PatientPhilippe Genet0Driss Chaoui1Virginie Masse2Ahmad Al Jijakli3Nina Arakelyan4Laurent Sutton5Service d’Hématologie, Centre Hospitalier Victor Dupouy, 69 Rue du Lieutenant-Colonel Prudhon, 95100 Argenteuil, FranceService d’Hématologie, Centre Hospitalier Victor Dupouy, 69 Rue du Lieutenant-Colonel Prudhon, 95100 Argenteuil, FranceService d’Hématologie, Centre Hospitalier Victor Dupouy, 69 Rue du Lieutenant-Colonel Prudhon, 95100 Argenteuil, FranceService d’Hématologie, Centre Hospitalier Victor Dupouy, 69 Rue du Lieutenant-Colonel Prudhon, 95100 Argenteuil, FranceService d’Hématologie, Centre Hospitalier Victor Dupouy, 69 Rue du Lieutenant-Colonel Prudhon, 95100 Argenteuil, FranceService d’Hématologie, Centre Hospitalier Victor Dupouy, 69 Rue du Lieutenant-Colonel Prudhon, 95100 Argenteuil, FranceCases of anaplastic large-cell lymphoma (ALCL) of T phenotype are sparse in the setting of HIV patients. We report herein a case of T-ALCL, with an advanced stage, pulmonary involvement, high HIV viral load, and low CD4 level. Anaplastic lymphoma kinase (ALK) protein expression was negative. Anthracyclin-based chemotherapy was unsuccessful. The literature review was performed focusing on incidence, clinical characteristics, prognosis, and physiopathology of ALCL in HIV patients. More data are needed to improve the knowledge of such cases and to define a better treatment approach.http://dx.doi.org/10.1155/2012/180204 |
| spellingShingle | Philippe Genet Driss Chaoui Virginie Masse Ahmad Al Jijakli Nina Arakelyan Laurent Sutton Anaplastic Large Cell Lymphoma Occurring in an HIV-Positive Patient Case Reports in Hematology |
| title | Anaplastic Large Cell Lymphoma Occurring in an HIV-Positive Patient |
| title_full | Anaplastic Large Cell Lymphoma Occurring in an HIV-Positive Patient |
| title_fullStr | Anaplastic Large Cell Lymphoma Occurring in an HIV-Positive Patient |
| title_full_unstemmed | Anaplastic Large Cell Lymphoma Occurring in an HIV-Positive Patient |
| title_short | Anaplastic Large Cell Lymphoma Occurring in an HIV-Positive Patient |
| title_sort | anaplastic large cell lymphoma occurring in an hiv positive patient |
| url | http://dx.doi.org/10.1155/2012/180204 |
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