Neurocysticercosis detected by targeted next-generation sequencing of cerebrospinal fluid: a case report

The patient, a middle-aged male with a long history of the disease, had experienced recurrent headaches for 26 years and episodic shaking of the right limb with slurred speech for the past month. He was previously diagnosed with cerebral cysticercosis and had shown improvement after anthelmintic tre...

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Main Authors: Xintong Ren, HuiQin Sun, Yanghong Cheng, Yunzhou Zhang, Daiquan Gao
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Neurology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2025.1504348/full
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author Xintong Ren
HuiQin Sun
Yanghong Cheng
Yunzhou Zhang
Daiquan Gao
author_facet Xintong Ren
HuiQin Sun
Yanghong Cheng
Yunzhou Zhang
Daiquan Gao
author_sort Xintong Ren
collection DOAJ
description The patient, a middle-aged male with a long history of the disease, had experienced recurrent headaches for 26 years and episodic shaking of the right limb with slurred speech for the past month. He was previously diagnosed with cerebral cysticercosis and had shown improvement after anthelmintic treatment. In recent years, he noted a resurgence of headaches. One month prior, he developed right limb shaking and occasional slurred speech. A clinical neurological examination was unremarkable, but cranial MRI and cerebrospinal fluid sequencing confirmed a diagnosis of cerebral cysticercosis. Anthelmintic treatment was administered, resulting in symptom improvement.
format Article
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publishDate 2025-04-01
publisher Frontiers Media S.A.
record_format Article
series Frontiers in Neurology
spelling doaj-art-e2f21728508548a3999ab9ea1a99e4a62025-08-20T02:12:53ZengFrontiers Media S.A.Frontiers in Neurology1664-22952025-04-011610.3389/fneur.2025.15043481504348Neurocysticercosis detected by targeted next-generation sequencing of cerebrospinal fluid: a case reportXintong Ren0HuiQin Sun1Yanghong Cheng2Yunzhou Zhang3Daiquan Gao4Department of Neurology, Xuanwu Hospital, Capital Medical University, Beijing, ChinaDepartment of Neurology, The Fifth People’s Hospital of Huai’an and the Affiliated Huai’an Hospital of Yangzhou University, Huai’an, ChinaEncephalopathy Rehabilitation Department, Yixian Hospital of Traditional Chinese Medicine, Baoding, ChinaDepartment of Neurology, Xuanwu Hospital, Capital Medical University, Beijing, ChinaDepartment of Neurology, Xuanwu Hospital, Capital Medical University, Beijing, ChinaThe patient, a middle-aged male with a long history of the disease, had experienced recurrent headaches for 26 years and episodic shaking of the right limb with slurred speech for the past month. He was previously diagnosed with cerebral cysticercosis and had shown improvement after anthelmintic treatment. In recent years, he noted a resurgence of headaches. One month prior, he developed right limb shaking and occasional slurred speech. A clinical neurological examination was unremarkable, but cranial MRI and cerebrospinal fluid sequencing confirmed a diagnosis of cerebral cysticercosis. Anthelmintic treatment was administered, resulting in symptom improvement.https://www.frontiersin.org/articles/10.3389/fneur.2025.1504348/fullneurocysticercosistargeted metagenomic next-generation sequencingseizurecerebrospinal fluidalbendazole
spellingShingle Xintong Ren
HuiQin Sun
Yanghong Cheng
Yunzhou Zhang
Daiquan Gao
Neurocysticercosis detected by targeted next-generation sequencing of cerebrospinal fluid: a case report
Frontiers in Neurology
neurocysticercosis
targeted metagenomic next-generation sequencing
seizure
cerebrospinal fluid
albendazole
title Neurocysticercosis detected by targeted next-generation sequencing of cerebrospinal fluid: a case report
title_full Neurocysticercosis detected by targeted next-generation sequencing of cerebrospinal fluid: a case report
title_fullStr Neurocysticercosis detected by targeted next-generation sequencing of cerebrospinal fluid: a case report
title_full_unstemmed Neurocysticercosis detected by targeted next-generation sequencing of cerebrospinal fluid: a case report
title_short Neurocysticercosis detected by targeted next-generation sequencing of cerebrospinal fluid: a case report
title_sort neurocysticercosis detected by targeted next generation sequencing of cerebrospinal fluid a case report
topic neurocysticercosis
targeted metagenomic next-generation sequencing
seizure
cerebrospinal fluid
albendazole
url https://www.frontiersin.org/articles/10.3389/fneur.2025.1504348/full
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