Pylephlebitis With Concomitant Fusobacterium Bacteremia: Lemierre's Syndrome Variant of the Gut

Pylephlebitis is a rare complication of intra-abdominal infections, and Fusobacterium, traditionally associated with thrombophlebitis of the internal jugular vein, is an extremely rare causative organism. This infection is associated with high morbidity and mortality, and there is still some controv...

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Main Authors: Mackenzie R. Barker, Mahmoud Khreis
Format: Article
Language:English
Published: American College of Physicians 2022-06-01
Series:Annals of Internal Medicine: Clinical Cases
Online Access:https://www.acpjournals.org/doi/10.7326/aimcc.2022.0176
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author Mackenzie R. Barker
Mahmoud Khreis
author_facet Mackenzie R. Barker
Mahmoud Khreis
author_sort Mackenzie R. Barker
collection DOAJ
description Pylephlebitis is a rare complication of intra-abdominal infections, and Fusobacterium, traditionally associated with thrombophlebitis of the internal jugular vein, is an extremely rare causative organism. This infection is associated with high morbidity and mortality, and there is still some controversy about management. Here, we report a patient who presented with pylephlebitis and Fusobacterium bacteremia and responded well to a short course of intravenous antibiotics, finished therapy in the outpatient setting, and made a full recovery. We also review relevant literature on treatment strategies including antibiotics, anticoagulation, and screening endoscopy.
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series Annals of Internal Medicine: Clinical Cases
spelling doaj-art-e2ee97484574456fa473464e5ac3159f2025-08-20T02:11:47ZengAmerican College of PhysiciansAnnals of Internal Medicine: Clinical Cases2767-76642022-06-011410.7326/aimcc.2022.0176Pylephlebitis With Concomitant Fusobacterium Bacteremia: Lemierre's Syndrome Variant of the GutMackenzie R. Barker0Mahmoud Khreis11Eastern Virginia Medical School, Norfolk, Virginia1Eastern Virginia Medical School, Norfolk, VirginiaPylephlebitis is a rare complication of intra-abdominal infections, and Fusobacterium, traditionally associated with thrombophlebitis of the internal jugular vein, is an extremely rare causative organism. This infection is associated with high morbidity and mortality, and there is still some controversy about management. Here, we report a patient who presented with pylephlebitis and Fusobacterium bacteremia and responded well to a short course of intravenous antibiotics, finished therapy in the outpatient setting, and made a full recovery. We also review relevant literature on treatment strategies including antibiotics, anticoagulation, and screening endoscopy.https://www.acpjournals.org/doi/10.7326/aimcc.2022.0176
spellingShingle Mackenzie R. Barker
Mahmoud Khreis
Pylephlebitis With Concomitant Fusobacterium Bacteremia: Lemierre's Syndrome Variant of the Gut
Annals of Internal Medicine: Clinical Cases
title Pylephlebitis With Concomitant Fusobacterium Bacteremia: Lemierre's Syndrome Variant of the Gut
title_full Pylephlebitis With Concomitant Fusobacterium Bacteremia: Lemierre's Syndrome Variant of the Gut
title_fullStr Pylephlebitis With Concomitant Fusobacterium Bacteremia: Lemierre's Syndrome Variant of the Gut
title_full_unstemmed Pylephlebitis With Concomitant Fusobacterium Bacteremia: Lemierre's Syndrome Variant of the Gut
title_short Pylephlebitis With Concomitant Fusobacterium Bacteremia: Lemierre's Syndrome Variant of the Gut
title_sort pylephlebitis with concomitant fusobacterium bacteremia lemierre s syndrome variant of the gut
url https://www.acpjournals.org/doi/10.7326/aimcc.2022.0176
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AT mahmoudkhreis pylephlebitiswithconcomitantfusobacteriumbacteremialemierressyndromevariantofthegut