Cholesterol effects on the tumor immune microenvironment: from fundamental concepts to mechanisms and implications
In many cancers, the tumor microenvironment is enriched with cholesterol due to increased biosynthesis and uptake by cancer cells, resulting in the accumulation of cholesterol, cholesterol esters, oxysterols and other metabolites with various functions. These molecules serve as structural components...
Saved in:
| Main Author: | Francisco Alejandro Lagunas-Rangel |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2025-04-01
|
| Series: | Frontiers in Oncology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fonc.2025.1579054/full |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Cholesterol-modulating effects of Korean red ginseng (KRG) targeting PCSK9 in hyperlipidemia
by: Chang Hwan Lee, et al.
Published: (2025-08-01) -
A novel pH-sensitive nanoparticles encapsulating anti-PD-1 antibody and MDK-siRNA overcome immune checkpoint blockade resistance in HCC via reshaping immunosuppressive TME
by: Hai Xu, et al.
Published: (2025-05-01) -
Tumor microenvironment as niche constructed by cancer stem cells: Breaking the ecosystem to combat cancer
by: Hao Zhong, et al.
Published: (2025-05-01) -
Sorafenib enhanced the function of myeloid-derived suppressor cells in hepatocellular carcinoma by facilitating PPARα-mediated fatty acid oxidation
by: Chunxiao Li, et al.
Published: (2025-01-01) -
Bidirectional Mendelian randomization analysis of causal relationships between immune cell traits and recurrent aphthous ulceration
by: XIE Xuejie, XU Jun, LIU Yuan, CHEN Yue, TANG Li, GULINUER Awuti
Published: (2025-04-01)