Cholesterol effects on the tumor immune microenvironment: from fundamental concepts to mechanisms and implications

In many cancers, the tumor microenvironment is enriched with cholesterol due to increased biosynthesis and uptake by cancer cells, resulting in the accumulation of cholesterol, cholesterol esters, oxysterols and other metabolites with various functions. These molecules serve as structural components...

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Bibliographic Details
Main Author: Francisco Alejandro Lagunas-Rangel
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Oncology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2025.1579054/full
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