Posterior Reversible Encephalopathy Syndrome Secondary to Hypercalcemia in a Teenager: A Case Report

This case details an atypical presentation of a common clinical condition, primary hyperparathyroidism. A 16-year-old girl with no medical history presented with status epilepticus and hypertension. She reported a 3-month history of asthenia, nausea, vomiting, polyuria, and weight loss, as well as a...

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Main Authors: Valeria Roldan, Catalina Aron-Said, Patricia Bejar, Jose Cotrina, Giancarlo Sante, Hector Sosa, Arturo E. Villena
Format: Article
Language:English
Published: American College of Physicians 2024-11-01
Series:Annals of Internal Medicine: Clinical Cases
Online Access:https://www.acpjournals.org/doi/10.7326/aimcc.2024.0426
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author Valeria Roldan
Catalina Aron-Said
Patricia Bejar
Jose Cotrina
Giancarlo Sante
Hector Sosa
Arturo E. Villena
author_facet Valeria Roldan
Catalina Aron-Said
Patricia Bejar
Jose Cotrina
Giancarlo Sante
Hector Sosa
Arturo E. Villena
author_sort Valeria Roldan
collection DOAJ
description This case details an atypical presentation of a common clinical condition, primary hyperparathyroidism. A 16-year-old girl with no medical history presented with status epilepticus and hypertension. She reported a 3-month history of asthenia, nausea, vomiting, polyuria, and weight loss, as well as an episode of sudden vision loss with persistent blurriness. Her serum calcium was 3.94 mmol/L and her level of parathyroid hormone was 28.16 pmol/L. T2-weighted magnetic resonance imaging of the brain revealed symmetrical bilateral occipito-parietal hyperintensities. Taken together, the clinical context and radiologic findings in this case suggested a diagnosis of posterior reversible encephalopathy syndrome. Hypercalcemia is a rare cause of posterior reversible encephalopathy syndrome.
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series Annals of Internal Medicine: Clinical Cases
spelling doaj-art-e2e8621491404247babcff0b8479c5ba2025-08-20T02:12:57ZengAmerican College of PhysiciansAnnals of Internal Medicine: Clinical Cases2767-76642024-11-0131110.7326/aimcc.2024.0426Posterior Reversible Encephalopathy Syndrome Secondary to Hypercalcemia in a Teenager: A Case ReportValeria Roldan0Catalina Aron-Said1Patricia Bejar2Jose Cotrina3Giancarlo Sante4Hector Sosa5Arturo E. Villena61Facultad de Medicina Alberto Hurtado, Universidad Peruana Cayetano Heredia, Lima, Peru1Facultad de Medicina Alberto Hurtado, Universidad Peruana Cayetano Heredia, Lima, Peru2Departamento de Endocrinología, Hospital Nacional Cayetano Heredia, Lima, Peru3Departamento de Medicina Interna, Hospital Nacional Cayetano Heredia, Lima, Peru3Departamento de Medicina Interna, Hospital Nacional Cayetano Heredia, Lima, Peru3Departamento de Medicina Interna, Hospital Nacional Cayetano Heredia, Lima, Peru2Departamento de Endocrinología, Hospital Nacional Cayetano Heredia, Lima, PeruThis case details an atypical presentation of a common clinical condition, primary hyperparathyroidism. A 16-year-old girl with no medical history presented with status epilepticus and hypertension. She reported a 3-month history of asthenia, nausea, vomiting, polyuria, and weight loss, as well as an episode of sudden vision loss with persistent blurriness. Her serum calcium was 3.94 mmol/L and her level of parathyroid hormone was 28.16 pmol/L. T2-weighted magnetic resonance imaging of the brain revealed symmetrical bilateral occipito-parietal hyperintensities. Taken together, the clinical context and radiologic findings in this case suggested a diagnosis of posterior reversible encephalopathy syndrome. Hypercalcemia is a rare cause of posterior reversible encephalopathy syndrome.https://www.acpjournals.org/doi/10.7326/aimcc.2024.0426
spellingShingle Valeria Roldan
Catalina Aron-Said
Patricia Bejar
Jose Cotrina
Giancarlo Sante
Hector Sosa
Arturo E. Villena
Posterior Reversible Encephalopathy Syndrome Secondary to Hypercalcemia in a Teenager: A Case Report
Annals of Internal Medicine: Clinical Cases
title Posterior Reversible Encephalopathy Syndrome Secondary to Hypercalcemia in a Teenager: A Case Report
title_full Posterior Reversible Encephalopathy Syndrome Secondary to Hypercalcemia in a Teenager: A Case Report
title_fullStr Posterior Reversible Encephalopathy Syndrome Secondary to Hypercalcemia in a Teenager: A Case Report
title_full_unstemmed Posterior Reversible Encephalopathy Syndrome Secondary to Hypercalcemia in a Teenager: A Case Report
title_short Posterior Reversible Encephalopathy Syndrome Secondary to Hypercalcemia in a Teenager: A Case Report
title_sort posterior reversible encephalopathy syndrome secondary to hypercalcemia in a teenager a case report
url https://www.acpjournals.org/doi/10.7326/aimcc.2024.0426
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