Myocarditis Related-COVID-19 mRNA Vaccination: A Narrative Review

The unprecedented impact of the coronavirus disease-19 (COVID-19) pandemic on society and the global economy has highlighted the urgent need for an effective and safe vaccine. One of the very rare side effects of this vaccine is myocarditis, which was realized to be a terrible complication of the CO...

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Main Authors: Idman Gushaendri, Faiza Shafia, Nany Hairunisa, Emad Yousif, Husnun Amalia
Format: Article
Language:English
Published: University of Anbar 2023-06-01
Series:Al-Anbar Medical Journal
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Online Access:https://amj.uoanbar.edu.iq/article_179060_40199a71a2a4a253062bd3ab73a162b6.pdf
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author Idman Gushaendri
Faiza Shafia
Nany Hairunisa
Emad Yousif
Husnun Amalia
author_facet Idman Gushaendri
Faiza Shafia
Nany Hairunisa
Emad Yousif
Husnun Amalia
author_sort Idman Gushaendri
collection DOAJ
description The unprecedented impact of the coronavirus disease-19 (COVID-19) pandemic on society and the global economy has highlighted the urgent need for an effective and safe vaccine. One of the very rare side effects of this vaccine is myocarditis, which was realized to be a terrible complication of the COVID-19 mRNA vaccine. A recent study showed an increase in 1824 events of myocarditis reported to VAERS, 383 (21.00%) reported after receiving a single dose of vaccine, then 956 (52.41%) after injection of the second dose. The most common complaint is chest pain that appears within 1 week after the injection. Young and male patients have a high incidence. The pathophysiology of post-mRNA vaccination myocarditis remains unclear, with one study hypothesizing it to be due to hypersensitivity myocarditis and another study suggesting another possible mechanism is molecular mimicry. The main aim of this literature review is to improve knowledge, prevention, and management, as well as determine the incidence between the COVID-19 mRNA vaccine and myocarditis.
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publishDate 2023-06-01
publisher University of Anbar
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series Al-Anbar Medical Journal
spelling doaj-art-e2e81d1811514b48b06bf26a8d70f6bb2025-08-20T02:38:42ZengUniversity of AnbarAl-Anbar Medical Journal2706-62072664-31542023-06-01191172310.33091/amj.2023.139728.1106179060Myocarditis Related-COVID-19 mRNA Vaccination: A Narrative ReviewIdman Gushaendri0Faiza Shafia1Nany Hairunisa2Emad Yousif3Husnun Amalia4Faculty of Medicine, Trisakti University, Jakarta, IndonesiaFaculty of Medicine, Trisakti University, Jakarta, IndonesiaDepartment of Occupational Medicine, Faculty of Medicine, Trisakti University, Jakarta, IndonesiaDepartment of Chemistry, College of Science, Al-Nahrain University, Baghdad, IraqDepartment of Ophthalmology, Faculty of Medicine, Trisakti University, Jakarta, IndonesiaThe unprecedented impact of the coronavirus disease-19 (COVID-19) pandemic on society and the global economy has highlighted the urgent need for an effective and safe vaccine. One of the very rare side effects of this vaccine is myocarditis, which was realized to be a terrible complication of the COVID-19 mRNA vaccine. A recent study showed an increase in 1824 events of myocarditis reported to VAERS, 383 (21.00%) reported after receiving a single dose of vaccine, then 956 (52.41%) after injection of the second dose. The most common complaint is chest pain that appears within 1 week after the injection. Young and male patients have a high incidence. The pathophysiology of post-mRNA vaccination myocarditis remains unclear, with one study hypothesizing it to be due to hypersensitivity myocarditis and another study suggesting another possible mechanism is molecular mimicry. The main aim of this literature review is to improve knowledge, prevention, and management, as well as determine the incidence between the COVID-19 mRNA vaccine and myocarditis.https://amj.uoanbar.edu.iq/article_179060_40199a71a2a4a253062bd3ab73a162b6.pdfcovid-19myocarditiscovid-19 mrna vaccine
spellingShingle Idman Gushaendri
Faiza Shafia
Nany Hairunisa
Emad Yousif
Husnun Amalia
Myocarditis Related-COVID-19 mRNA Vaccination: A Narrative Review
Al-Anbar Medical Journal
covid-19
myocarditis
covid-19 mrna vaccine
title Myocarditis Related-COVID-19 mRNA Vaccination: A Narrative Review
title_full Myocarditis Related-COVID-19 mRNA Vaccination: A Narrative Review
title_fullStr Myocarditis Related-COVID-19 mRNA Vaccination: A Narrative Review
title_full_unstemmed Myocarditis Related-COVID-19 mRNA Vaccination: A Narrative Review
title_short Myocarditis Related-COVID-19 mRNA Vaccination: A Narrative Review
title_sort myocarditis related covid 19 mrna vaccination a narrative review
topic covid-19
myocarditis
covid-19 mrna vaccine
url https://amj.uoanbar.edu.iq/article_179060_40199a71a2a4a253062bd3ab73a162b6.pdf
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AT faizashafia myocarditisrelatedcovid19mrnavaccinationanarrativereview
AT nanyhairunisa myocarditisrelatedcovid19mrnavaccinationanarrativereview
AT emadyousif myocarditisrelatedcovid19mrnavaccinationanarrativereview
AT husnunamalia myocarditisrelatedcovid19mrnavaccinationanarrativereview