Optical Imaging Biomarkers of Drug-Induced Vascular Injury

Optical Imaging Biomarkers of Drug-Induced Vascular Injury

Drug-induced vascular injury (DIVI), defined as arterial medial degeneration/necrosis usually associated with perivascular inflammation, is frequently observed in the mesenteric arteries of rats but the relevance to humans remains a hurdle for drug development. Here, we describe the evaluation of co...

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Bibliographic Details
Main Authors: Shu-An Lin MS, Donna L. Suresch, Brett Connolly, Gebre Mesfin, Raymond J. Gonzalez, Manishkumar R. Patel, Diane Shevell, Timothy Johnson, Bohumil Bednar
Format: Article
Language:English
Published: SAGE Publishing 2015-01-01
Series:Molecular Imaging
Online Access:https://doi.org/10.2310/7290.2014.00054
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