Regional profiling reveals a distinct glioblastoma infiltrative margin proteome

Regional profiling reveals a distinct glioblastoma infiltrative margin proteome

Abstract Isocitrate dehydrogenase wild-type glioblastoma, a malignant brain tumour of glial origin, confers a poor prognosis with a median survival of 12 to 16 months from diagnosis. Glioblastomas are aggressive tumours that rapidly proliferate and diffusely infiltrate surrounding brain tissue. Curr...

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Bibliographic Details
Main Authors: Artur Kocon, Stuart J. Smith, Benito Morentin, Luis F. Callado, Wayne Carter, Ruman Rahman
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Glioblastoma
2D-PAGE
Proteomics
Tandem mass spectrometry
Online Access:https://doi.org/10.1038/s41598-025-09228-z
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