Barrett’s Esophagus: Is It All That Bad?

An alarmingly rapid rise in the number of adenocarcinomas at the level of the gastroesophageal junction and distal esophagus has been noted over the past two decades. Intestinal metaplasia is considered to be the main precursor lesion for such adenocarcinomas. Given the low five-year survival rate i...

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Main Author: GNJ Tytgat
Format: Article
Language:English
Published: Wiley 1999-01-01
Series:Canadian Journal of Gastroenterology
Online Access:http://dx.doi.org/10.1155/1999/612574
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author GNJ Tytgat
author_facet GNJ Tytgat
author_sort GNJ Tytgat
collection DOAJ
description An alarmingly rapid rise in the number of adenocarcinomas at the level of the gastroesophageal junction and distal esophagus has been noted over the past two decades. Intestinal metaplasia is considered to be the main precursor lesion for such adenocarcinomas. Given the low five-year survival rate in patients with advanced esophageal cancer, strategies for early detection have been developed. Because superficial cancers only rarely cause symptoms, detection of cancer at such an early curable state can only be achieved through surveillance of patients at risk. Therefore, implementation of an endoscopic surveillance program for patients in whom intestinal metaplasia has been detected in the distal esophagus or at the esophagogastric junction seems to be a reasonable option.
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spelling doaj-art-e2dc0b5cec124c33a1920b89ca0453802025-02-03T06:42:27ZengWileyCanadian Journal of Gastroenterology0835-79001999-01-0113538538810.1155/1999/612574Barrett’s Esophagus: Is It All That Bad?GNJ Tytgat0Academic Medical Center, Department of Gastroenterology and Hepatology, Amsterdam, The NetherlandsAn alarmingly rapid rise in the number of adenocarcinomas at the level of the gastroesophageal junction and distal esophagus has been noted over the past two decades. Intestinal metaplasia is considered to be the main precursor lesion for such adenocarcinomas. Given the low five-year survival rate in patients with advanced esophageal cancer, strategies for early detection have been developed. Because superficial cancers only rarely cause symptoms, detection of cancer at such an early curable state can only be achieved through surveillance of patients at risk. Therefore, implementation of an endoscopic surveillance program for patients in whom intestinal metaplasia has been detected in the distal esophagus or at the esophagogastric junction seems to be a reasonable option.http://dx.doi.org/10.1155/1999/612574
spellingShingle GNJ Tytgat
Barrett’s Esophagus: Is It All That Bad?
Canadian Journal of Gastroenterology
title Barrett’s Esophagus: Is It All That Bad?
title_full Barrett’s Esophagus: Is It All That Bad?
title_fullStr Barrett’s Esophagus: Is It All That Bad?
title_full_unstemmed Barrett’s Esophagus: Is It All That Bad?
title_short Barrett’s Esophagus: Is It All That Bad?
title_sort barrett s esophagus is it all that bad
url http://dx.doi.org/10.1155/1999/612574
work_keys_str_mv AT gnjtytgat barrettsesophagusisitallthatbad