Passenger Lymphocyte Syndrome and Liver Transplantation
The authors reviewed the passenger lymphocyte syndrome (PLS) that has appeared after transplantation. The definition, mechanism, serological, clinical features, and treatment for PLS after solid organ transplantation, especially liver transplantation, are described. The PLS refers to the clinical ph...
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| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2008-01-01
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| Series: | Clinical and Developmental Immunology |
| Online Access: | http://dx.doi.org/10.1155/2008/715769 |
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| _version_ | 1850167244329320448 |
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| author | Maxime Audet Fabrizio Panaro Tullio Piardi Ping Huang Murat Cag Jacques Cinqualbre Philippe Wolf |
| author_facet | Maxime Audet Fabrizio Panaro Tullio Piardi Ping Huang Murat Cag Jacques Cinqualbre Philippe Wolf |
| author_sort | Maxime Audet |
| collection | DOAJ |
| description | The authors reviewed the passenger lymphocyte syndrome (PLS) that has appeared after transplantation. The definition, mechanism, serological, clinical features, and treatment for PLS after solid organ transplantation, especially liver transplantation, are described. The PLS refers to the clinical phenomenon of alloimmune hemolysis resulting from the adoptive transfer of viable lymphocytes from donor during solid organ or hematopoietic stem cell transplant. Sometimes, it is very severe and may cause “unexplained” hemolysis during the postoperative period.
The authors reviewed literature about the PLS in liver transplantation. |
| format | Article |
| id | doaj-art-e2dba1067e8948278cd434c40cafb3f6 |
| institution | OA Journals |
| issn | 1740-2522 1740-2530 |
| language | English |
| publishDate | 2008-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Clinical and Developmental Immunology |
| spelling | doaj-art-e2dba1067e8948278cd434c40cafb3f62025-08-20T02:21:14ZengWileyClinical and Developmental Immunology1740-25221740-25302008-01-01200810.1155/2008/715769715769Passenger Lymphocyte Syndrome and Liver TransplantationMaxime Audet0Fabrizio Panaro1Tullio Piardi2Ping Huang3Murat Cag4Jacques Cinqualbre5Philippe Wolf6Centre de Chirurgie Viscérale et de Transplantation, Hôpital de Hautepierre, Hopitaux Universitaires de Strasbourg-Université Louis Pasteur, Avenue Molière, 67200 Strasbourg, FranceCentre de Chirurgie Viscérale et de Transplantation, Hôpital de Hautepierre, Hopitaux Universitaires de Strasbourg-Université Louis Pasteur, Avenue Molière, 67200 Strasbourg, FranceCentre de Chirurgie Viscérale et de Transplantation, Hôpital de Hautepierre, Hopitaux Universitaires de Strasbourg-Université Louis Pasteur, Avenue Molière, 67200 Strasbourg, FranceCentre de Chirurgie Viscérale et de Transplantation, Hôpital de Hautepierre, Hopitaux Universitaires de Strasbourg-Université Louis Pasteur, Avenue Molière, 67200 Strasbourg, FranceCentre de Chirurgie Viscérale et de Transplantation, Hôpital de Hautepierre, Hopitaux Universitaires de Strasbourg-Université Louis Pasteur, Avenue Molière, 67200 Strasbourg, FranceCentre de Chirurgie Viscérale et de Transplantation, Hôpital de Hautepierre, Hopitaux Universitaires de Strasbourg-Université Louis Pasteur, Avenue Molière, 67200 Strasbourg, FranceCentre de Chirurgie Viscérale et de Transplantation, Hôpital de Hautepierre, Hopitaux Universitaires de Strasbourg-Université Louis Pasteur, Avenue Molière, 67200 Strasbourg, FranceThe authors reviewed the passenger lymphocyte syndrome (PLS) that has appeared after transplantation. The definition, mechanism, serological, clinical features, and treatment for PLS after solid organ transplantation, especially liver transplantation, are described. The PLS refers to the clinical phenomenon of alloimmune hemolysis resulting from the adoptive transfer of viable lymphocytes from donor during solid organ or hematopoietic stem cell transplant. Sometimes, it is very severe and may cause “unexplained” hemolysis during the postoperative period. The authors reviewed literature about the PLS in liver transplantation.http://dx.doi.org/10.1155/2008/715769 |
| spellingShingle | Maxime Audet Fabrizio Panaro Tullio Piardi Ping Huang Murat Cag Jacques Cinqualbre Philippe Wolf Passenger Lymphocyte Syndrome and Liver Transplantation Clinical and Developmental Immunology |
| title | Passenger Lymphocyte Syndrome and Liver Transplantation |
| title_full | Passenger Lymphocyte Syndrome and Liver Transplantation |
| title_fullStr | Passenger Lymphocyte Syndrome and Liver Transplantation |
| title_full_unstemmed | Passenger Lymphocyte Syndrome and Liver Transplantation |
| title_short | Passenger Lymphocyte Syndrome and Liver Transplantation |
| title_sort | passenger lymphocyte syndrome and liver transplantation |
| url | http://dx.doi.org/10.1155/2008/715769 |
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