The formulated microbicide RC-101 was safe and antivirally active following intravaginal application in pigtailed macaques.

The formulated microbicide RC-101 was safe and antivirally active following intravaginal application in pigtailed macaques.

<h4>Background</h4>RC-101 is a congener of the antiretroviral peptide retrocyclin, which we and others have reported is active against clinical HIV-1 isolates from all major clades, does not hemagglutinate, and is non-toxic and non-inflammatory in cervicovaginal cell culture. Herein, fil...

Full description

Saved in:
Bibliographic Details
Main Authors: Alexander M Cole, Dorothy L Patton, Lisa C Rohan, Amy L Cole, Yvonne Cosgrove-Sweeney, Nicole A Rogers, Deena Ratner, Alexandra B Sassi, Carol Lackman-Smith, Patrick Tarwater, Bharat Ramratnam, Piotr Ruchala, Robert I Lehrer, Alan J Waring, Phalguni Gupta
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-11-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0015111&type=printable
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items