A whole blood assay for antibody dependent phagocytosis of Plasmodium falciparum infected erythrocytes

A whole blood assay for antibody dependent phagocytosis of Plasmodium falciparum infected erythrocytes

Abstract Background Antibodies are used to protect against Plasmodium falciparum malaria. One antibody target, the variant surface antigens, is expressed on infected erythrocytes (IEs). Antibodies to these antigens can either block IE sequestration in the tissues, facilitate natural killer cell-medi...

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Main Authors: Dilini Rathnayake, Wina Hasang, Alexander Macpherson, HongHua Ding, Laurens Manning, Moses Laman, Maria Ome-Kaius, Holger W. Unger, Feiko Ter Kuile, Mwayi Madanitsa, Bruce Wines, P. Mark Hogarth, Elizabeth H. Aitken, Stephen J. Rogerson
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Communications Medicine
Online Access:https://doi.org/10.1038/s43856-025-00989-2
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