BRCA1, BRCA2 mutations — future of predictive oncology: a review of literature

In recent years, it has been demonstrated that breast cancer arising in BRCA1 and BRCA2 mutation carriers differs in its morphological, immuno- phenotypic and molecular characteristics from sporadic breast cancer. In addition to improving our understanding of the biology of hereditary breast cancer,...

Full description

Saved in:
Bibliographic Details
Main Authors: V. N. Dmitriev, I. V. Sukhoterin, I. I. Zybenko, T. V. Dmitrieva
Format: Article
Language:Russian
Published: ABV-press 2014-07-01
Series:Опухоли женской репродуктивной системы
Subjects:
Online Access:https://ojrs.abvpress.ru/ojrs/article/view/71
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1849399076345348096
author V. N. Dmitriev
I. V. Sukhoterin
I. I. Zybenko
T. V. Dmitrieva
author_facet V. N. Dmitriev
I. V. Sukhoterin
I. I. Zybenko
T. V. Dmitrieva
author_sort V. N. Dmitriev
collection DOAJ
description In recent years, it has been demonstrated that breast cancer arising in BRCA1 and BRCA2 mutation carriers differs in its morphological, immuno- phenotypic and molecular characteristics from sporadic breast cancer. In addition to improving our understanding of the biology of hereditary breast cancer, the recognition of these differences could also be used to predict BRCA mutation status in a given group of patients.
format Article
id doaj-art-e2d1f2f8890f4c86aefd1b7656f93488
institution Kabale University
issn 1994-4098
1999-8627
language Russian
publishDate 2014-07-01
publisher ABV-press
record_format Article
series Опухоли женской репродуктивной системы
spelling doaj-art-e2d1f2f8890f4c86aefd1b7656f934882025-08-20T03:38:25ZrusABV-pressОпухоли женской репродуктивной системы1994-40981999-86272014-07-0101131610.17650/1994-4098-2012-0-1-13-1686BRCA1, BRCA2 mutations — future of predictive oncology: a review of literatureV. N. Dmitriev0I. V. Sukhoterin1I. I. Zybenko2T. V. Dmitrieva3Belgorod State National Research UniversityBelgorod State National Research UniversityBelgorod State National Research UniversityBelgorod State National Research UniversityIn recent years, it has been demonstrated that breast cancer arising in BRCA1 and BRCA2 mutation carriers differs in its morphological, immuno- phenotypic and molecular characteristics from sporadic breast cancer. In addition to improving our understanding of the biology of hereditary breast cancer, the recognition of these differences could also be used to predict BRCA mutation status in a given group of patients.https://ojrs.abvpress.ru/ojrs/article/view/71brca1brca2 mutationshereditary breast cancerovarian cancer
spellingShingle V. N. Dmitriev
I. V. Sukhoterin
I. I. Zybenko
T. V. Dmitrieva
BRCA1, BRCA2 mutations — future of predictive oncology: a review of literature
Опухоли женской репродуктивной системы
brca1
brca2 mutations
hereditary breast cancer
ovarian cancer
title BRCA1, BRCA2 mutations — future of predictive oncology: a review of literature
title_full BRCA1, BRCA2 mutations — future of predictive oncology: a review of literature
title_fullStr BRCA1, BRCA2 mutations — future of predictive oncology: a review of literature
title_full_unstemmed BRCA1, BRCA2 mutations — future of predictive oncology: a review of literature
title_short BRCA1, BRCA2 mutations — future of predictive oncology: a review of literature
title_sort brca1 brca2 mutations future of predictive oncology a review of literature
topic brca1
brca2 mutations
hereditary breast cancer
ovarian cancer
url https://ojrs.abvpress.ru/ojrs/article/view/71
work_keys_str_mv AT vndmitriev brca1brca2mutationsfutureofpredictiveoncologyareviewofliterature
AT ivsukhoterin brca1brca2mutationsfutureofpredictiveoncologyareviewofliterature
AT iizybenko brca1brca2mutationsfutureofpredictiveoncologyareviewofliterature
AT tvdmitrieva brca1brca2mutationsfutureofpredictiveoncologyareviewofliterature